Cell surface-based differentiation of cell types and cancer states using a gold nanoparticle-GFP based sensing array

Bajaj, Avinash; Rana, Subinoy; Miranda, Oscar R.; Yawe, Joseph C.; Rotello, Vincent M.

Cell surface-based differentiation of cell types and cancer states using a gold nanoparticle-GFP based sensing array

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Cell surface-based differentiation of cell types and cancer states using a gold nanoparticle-GFP based sensing array.pdf (261.1 KB)

Date

2010

Authors

Publisher

Chemical Science

Abstract

Gold nanoparticle-green fluorescent protein (NP-GFP) based arrays have been created for rapid identification of mammalian cells on the basis of cell surface properties. Highly reproducible characteristic patterns were obtained from different cell types enabling the identification of cell types and cancer states. Using these arrays we could differentiate between isogenic normal, cancer and metastatic cell types using only ∼5000 cells.

Keywords

Sensing array, Cell surface-based differentiation, Cancer states, Gold nanoparticle-GFP

Citation

Bajaj, A., Rana, S., Miranda, O. R., Yawe, J. C., Jerry, D. J., Bunz, U. H., & Rotello, V. M. (2010). Cell surface-based differentiation of cell types and cancer states using a gold nanoparticle-GFP based sensing array. Chemical Science, 1(1), 134-138.https://doi.org/10.1039/C0SC00165A

URI

https://nru.uncst.go.ug/handle/123456789/8466

Collections

Medical and Health Sciences

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