Efavirenz poisoning in a 12 year old HIV negative African boy

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dc.contributor.authorNazziwa, Rose
dc.contributor.authorSekadde, Moorine
dc.contributor.authorKanyike, Francis
dc.contributor.authorWobudeya, Eric
dc.contributor.authorNabukeera-Barungi, Nicolette
dc.date.accessioned2022-12-22T08:26:46Z
dc.date.available2022-12-22T08:26:46Z
dc.date.issued2012
dc.description.abstractEfavirenz is an oral antiretroviral drug in the class of non nucleoside reverse transcriptase inhibitors. Toxicity at therapeutic doses has been documented but there is scarcity of data on presentation and management of Efavirenz overdose. We describe a case of Efavirenz poisoning in a 12-year old HIV Negative African boy with a very unique presentation after ingesting 3 grams of Efavirenz as a single dose. The most prominent problems were burning sensation in the throat immediately after ingestion then visual impairment one hour later then tremors, screaming at night and motor deficits in lower limbs for 5 days before admission. His medical history, physical exam and investigations revealed no other cause of his presentation other than the EFV. Unfortunately, it was not possible to do EFV levels. He was given supportive treatment and 10 days later he was completely well.en_US
dc.identifier.citationNazziwa, R., Sekadde, M., Kanyike, F., Wobudeya, E., & Nabukeera-Barungi, N. (2012). Efavirenz poisoning in a 12 year old HIV negative African boy. Pan African Medical Journal, 12(1).en_US
dc.identifier.issn1937-8688.
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/6490
dc.language.isoenen_US
dc.publisherPan African Medical Journalen_US
dc.subjectEfavirenzen_US
dc.subjectpoisoningen_US
dc.subjectintoxicationen_US
dc.subjectadverse reactionen_US
dc.subjectHIVen_US
dc.titleEfavirenz poisoning in a 12 year old HIV negative African boyen_US
dc.typeArticleen_US
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