Medicinal Plants Used as Snake Venom Antidotes in East African Community: Review and Assessment of Scientific Evidences

Simple item page
dc.contributor.authorOmara, Timothy
dc.contributor.authorKiwanuka Nakiguli, Caroline
dc.contributor.authorNaiyl, Rania Awad
dc.contributor.authorAtieno Opondo, Florence
dc.contributor.authorOtieno, Sadia Benard
dc.contributor.authorNdiege, Merab Lilian
dc.contributor.authorMbabazi, Immaculate
dc.contributor.authorNassazi, Winfred
dc.contributor.authorNteziyaremye, Papias
dc.contributor.authorKagoya, Sarah
dc.contributor.authorOkwir, Augastine
dc.contributor.authorEtimu, Edmond
dc.date.accessioned2023-04-14T18:32:26Z
dc.date.available2023-04-14T18:32:26Z
dc.date.issued2021
dc.description.abstractPoisonous snake envenomation is a complex neglected health problem implicated in mortality, disability, psychological morbidity, and socio-economic losses recorded worldwide. An antivenin serum, the only medically recommended treatment for snakebites, has several drawbacks including, hypersensitivity, inability to prevent local tissue damage, are scarce and unaffordable in most snakebite endemic areas. In many rural communities all over the world, plants have been utilized for managing snakebites. This review seeks to identify plants reported as antivenom remedies in the East Africa and the scientific studies thereof which could support their use in the treatment of snake envenomation. A review of scientific articles was undertaken to identify information on traditional knowledge of medicinal plants used to treat snake envenomation in East Africa and their antivenom efficacy. A total of 361 plant species were retrieved to have been reported as traditional therapies for snakebites in East Africa. The review identified distinct cases of doctrine of signatures and zoopharmacognosy in snakes using Opilia amentacea, Hugonia castaneifolia and Microglossa pyrifolia respectively. Evaluations of the antivenom efficacy of 44 species (12.2%) have been done globally, and most species found to be effective in neutralizing the lethal activities of snake venoms. Ethnomedicinal plants play a revered holistic role in East African antisnake venom therapy. Conyza sumatrensis, Hyptis pectinata, Justicia betonica, and Maesa lanceolata used to treat specific snakebites merit further studies.en_US
dc.identifier.citationOmara, T., Nakiguli, C. K., Naiyl, R. A., Opondo, F. A., Otieno, S. B., Ndiege, M. L., ... & Etimu, E. (2021). Medicinal plants used as snake venom antidotes in East African Community: review and assessment of scientific evidences. J Med Chem Sci, 4(2), 107-144. DOI:10.26655/JMCHEMSCI.2021.2.4en_US
dc.identifier.issn10.26655/JMCHEMSCI.2021.2.4
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8478
dc.language.isoenen_US
dc.publisherJournal of Medicinal and Chemical Sciencesen_US
dc.subjectAntivenom plantsen_US
dc.subjectNeglected tropical diseaseen_US
dc.subjectSnakebitesen_US
dc.subjectSub-Saharan Africaen_US
dc.subjectTraditional medicineen_US
dc.titleMedicinal Plants Used as Snake Venom Antidotes in East African Community: Review and Assessment of Scientific Evidencesen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Medicinal Plants Used as Snake Venom Antidotes in East African.pdf
Size:
2.72 MB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Natural Sciences