Genome-Wide Sequencing Reveals Two Major Sub-Lineages in the Genetically Monomorphic Pathogen Xanthomonas Campestris Pathovar Musacearum.

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dc.contributor.authorWasukira, Arthur
dc.contributor.authorTayebwa, Johnbosco
dc.contributor.authorThwaites, Richard
dc.contributor.authorPaszkiewicz, Konrad
dc.contributor.authorAritua, Valente
dc.contributor.authorKubiriba, Jerome
dc.contributor.authorSmith, Julian
dc.contributor.authorGrant, Murray
dc.contributor.authorStudholme, David J.
dc.date.accessioned2022-05-27T15:24:42Z
dc.date.available2022-05-27T15:24:42Z
dc.date.issued2012
dc.description.abstractThe bacterium Xanthomonas campestris pathovar musacearum (Xcm) is the causal agent of banana Xanthomonas wilt (BXW). This disease has devastated economies based on banana and plantain crops (Musa species) in East Africa. Here we use genome-wide sequencing to discover a set of single-nucleotide polymorphisms (SNPs) among East African isolates of Xcm. These SNPs have potential as molecular markers for phylogeographic studies of the epidemiology and spread of the pathogen. Our analysis reveals two major sub-lineages of the pathogen, suggesting that the current outbreaks of BXW on Musa species in the region may have more than one introductory event, perhaps from Ethiopia. Also, based on comparisons of genome-wide sequence data from multiple isolates of Xcm and multiple strains of X. vasicola pathovar vasculorum, we identify genes specific to Xcm that could be used to specifically detect Xcm by PCR-based methods.en_US
dc.identifier.citationWasukira, A., Tayebwa, J., Thwaites, R., Paszkiewicz, K., Aritua, V., Kubiriba, J., ... & Studholme, DJ (2012). Genome-wide sequencing reveals two major sub-lineages in the genetically monomorphic pathogen Xanthomonas campestris pathovar musacearum. Genes, doi:10.3390/genes3030361en_US
dc.identifier.other10.3390/genes3030361
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/3592
dc.language.isoenen_US
dc.publisherGenesen_US
dc.subjectBanana Xanthomonas wilten_US
dc.subjectWhole-genome sequencingen_US
dc.subjectSNPen_US
dc.subjectMolecular markersen_US
dc.subjectEnsete ventricosumen_US
dc.subjectXanthomonas vasicolaen_US
dc.titleGenome-Wide Sequencing Reveals Two Major Sub-Lineages in the Genetically Monomorphic Pathogen Xanthomonas Campestris Pathovar Musacearum.en_US
dc.typeArticleen_US
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