Validity of caregivers’ reports on prior use of antibacterials in children under five years presenting to health facilities in Gulu, northern Uganda
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Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
PLoS ONE
Abstract
Given the frequent initiation of antibacterial treatment at home by caregivers of children
under five years in low-income countries, there is a need to find out whether caregivers’
reports of prior antibacterial intake by their children before being brought to the healthcare
facility are accurate. The aim of this study was to describe and validate caregivers’ reported
use of antibacterials by their children prior to seeking care at the healthcare facility.
Methods
A cross sectional study was conducted among children under five years seeking care at
healthcare facilities in Gulu district, northern Uganda. Using a researcher administered
questionnaire, data were obtained from caregivers regarding reported prior antibacterial
intake in their children. These reports were validated by comparing them to common antibacterial
agents detected in blood and urine samples from the children using liquid chromatography
with tandem mass spectrometry (LC-MS/MS) methods.
Description
Keywords
Caregivers’ reports, Antibacterials, Children under five years, Health facilities, Gulu, Northern Uganda
Citation
Lanyero H, Ocan M, Obua C, Stålsby Lundborg C, Agaba K, Kalyango JN, et al. (2021) Validity of caregivers’ reports on prior use of antibacterials in children under five years presenting to health facilities in Gulu, northern Uganda. PLoS ONE 16(9): e0257328. https://doi. org/10.1371/journal.pone.0257328