Association between tuberculosis in men and social network structure in Kampala, Uganda

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dc.contributor.authorMiller, Paige B.
dc.contributor.authorZalwango, Sarah
dc.contributor.authorGaliwango, Ronald
dc.contributor.authorKakaire, Robert
dc.contributor.authorSekandi, Juliet
dc.contributor.authorSteinbaum, Lauren
dc.contributor.authorDrake, John M.
dc.contributor.authorWhalen, Christopher C.
dc.contributor.authorKiwanuka, Noah
dc.date.accessioned2022-06-07T06:02:37Z
dc.date.available2022-06-07T06:02:37Z
dc.date.issued2021
dc.description.abstractGlobally, tuberculosis disease (TB) is more common among males than females. Recent research proposes that differences in social mixing by sex could alter infection patterns in TB. We examine evidence for two mechanisms by which social-mixing could increase men’s contact rates with TB cases. First, men could be positioned in social networks such that they contact more people or social groups. Second, preferential mixing by sex could prime men to have more exposure to TB cases. Methods: We compared the networks of male and female TB cases and healthy matched controls living in Kampala, Uganda. Specifically, we estimated their positions in social networks (network distance to TB cases, degree, betweenness, and closeness) and assortativity patterns (mixing with adult men, women, and children inside and outside the household). Results: The observed network consisted of 11,840 individuals. There were few differences in estimates of node position by sex. We found distinct mixing patterns by sex and TB disease status including that TB cases have proportionally more adult male contacts and fewer contacts with children. Conclusions: This analysis used a network approach to study how social mixing patterns are associated with TB disease. Understanding these mechanisms may have implications for designing targeted intervention strategies in high-burden populations.en_US
dc.identifier.citationMiller, P. B., Zalwango, S., Galiwango, R., Kakaire, R., Sekandi, J., Steinbaum, L., ... & Kiwanuka, N. (2021). Association between tuberculosis in men and social network structure in Kampala, Uganda. BMC infectious diseases, 21(1), 1-9. https://doi.org/10.1186/s12879-021-06475-zen_US
dc.identifier.urihttps://doi.org/10.1186/s12879-021-06475-z
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/3795
dc.language.isoenen_US
dc.publisherBMC infectious diseasesen_US
dc.subjectTuberculosisen_US
dc.subjectSocial networken_US
dc.subjectMale-biasen_US
dc.subjectContact patternsen_US
dc.titleAssociation between tuberculosis in men and social network structure in Kampala, Ugandaen_US
dc.typeArticleen_US
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