Feasibility of collecting and processing of COVID-19 convalescent plasma for treatment of COVID-19 in Uganda

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dc.contributor.authorMuttamba, Winters
dc.contributor.authorLusiba, John
dc.contributor.authorNamakula, Loryndah Olive
dc.contributor.authorByakika-Kibwika, Pauline
dc.contributor.authorSsali, Francis
dc.contributor.authorDdungu, Henry
dc.contributor.authorMugenyi, Levicatus
dc.contributor.authorKiwanuka, Noah
dc.contributor.authorSekibira, Rogers
dc.contributor.authorKityo, Cissy
dc.contributor.authorKeyune, Dorothy
dc.contributor.authorAcana, Susan
dc.contributor.authorMusinguzi, Ambrose
dc.contributor.authorMasasi, Ayub
dc.contributor.authorByamugisha, Joseph
dc.contributor.authorMpanju, David
dc.contributor.authorMusoki, Walter Jack
dc.contributor.authorTukamuhebwa, Hellen Aanyu
dc.contributor.authorNakwagala, Fred
dc.contributor.authorSentalo Bagaya, Bernard
dc.contributor.authorKayongo, Alex
dc.contributor.authorKimuli, Ivan
dc.contributor.authorNantanda, Rebecca
dc.contributor.authorKatagira, Winceslaus
dc.contributor.authorBuregyeya, Esther
dc.contributor.authorByanyima, Rosemary
dc.contributor.authorByarugaba, Baterana
dc.contributor.authorSiddharthan, Trishul
dc.contributor.authorMwebesa, Henry
dc.contributor.authorCharles, Olaro
dc.contributor.authorLutaakome Joloba, Moses
dc.contributor.authorBazeyo, William
dc.contributor.authorKirenga, Bruce
dc.date.accessioned2022-01-14T07:07:13Z
dc.date.available2022-01-14T07:07:13Z
dc.date.issued2021
dc.description.abstractEvidence that supports the use of COVID-19 convalescent plasma (CCP) for treatment of COVID-19 is increasingly emerging. However, very few African countries have undertaken the collection and processing of CCP. The aim of this study was to assess the feasibility of collecting and processing of CCP, in preparation for a randomized clinical trial of CCP for treatment of COVID-19 in Uganda. Methods In a cross-sectional study, persons with documented evidence of recovery from COVID-19 in Uganda were contacted and screened for blood donation via telephone calls. Those found eligible were asked to come to the blood donation centre for further screening and consent. Whole blood collection was undertaken from which plasma was processed. Plasma was tested for transfusion transmissible infections (TTIs) and anti-SARS CoV-2 antibody titers. SARS-CoV-2 testing was also done on nasopharyngeal swabs from the donors.en_US
dc.identifier.citationMuttamba W, Lusiba J, Namakula LO, Byakika-Kibwika P, Ssali F, Ddungu H, et al. (2021) Feasibility of collecting and processing of COVID- 19 convalescent plasma for treatment of COVID-19 in Uganda. PLoS ONE 16(6): e0252306. https://doi. org/10.1371/journal.pone.0252306en_US
dc.identifier.urihttps://doi. org/10.1371/journal.pone.0252306
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1273
dc.language.isoenen_US
dc.publisherPLoS ONEen_US
dc.subjectCOVID-19 convalescent plasmaen_US
dc.subjectTreatmenten_US
dc.subjectCOVID-19en_US
dc.subjectUgandaen_US
dc.titleFeasibility of collecting and processing of COVID-19 convalescent plasma for treatment of COVID-19 in Ugandaen_US
dc.typeArticleen_US
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