Foot-and-Mouth Disease Virus Serotype SAT 3 in Long-Horned Ankole Calf, Uganda
Loading...
Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Emerging Infectious Diseases
Abstract
Foot-and-mouth disease (FMD) remains one of the most
economically important diseases of livestock, costing
≈US $10 billion annually (1). Outbreaks occur in many
countries, and normally disease-free countries can incur
huge costs after incursions (e.g., the United Kingdom in
2001). The disease results from infection with FMD virus
(FMDV, the prototypic aphthovirus within the Picornaviridae
family) (2). Seven serotypes of FMDV are known; serotypes
O and A are widely distributed, and the Southern
African Territories (SAT) serotypes (1, 2, and 3) usually are
restricted to Africa. Serotype Asia 1 has never circulated
within Africa; serotype C has not been identified anywhere
since 2005 (2,3). SAT 3 FMDV is the least well–characterized
serotype; the most recent incidence of SAT 3 reported
by the FMD World Reference Laboratory (Pirbright
Institute, Woking, UK) was in buffalo within the Kruger
National Park (South Africa) in 2006. In contrast, SAT 1
and SAT 2 FMDVs are much more common; a major incursion
of SAT 2 into the Middle East occurred in 2012
(4), and outbreaks caused by these serotypes have occurred
in many African countries (http://www.wrlfmd.org/fmd_
genotyping/2013.htm).
In Uganda, FMD is endemic, and serotypes O and SAT
2 are the most common. In Uganda, SAT 3 FMDV was
most recently identified in 1997 in buffalo in the Queen Elizabeth National Park (QENP) (5). SAT 1 and SAT 2
viruses were isolated from buffalo in QENP in 2006, and
serologic test results indicated the presence of antibodies
against SAT 3 virus; however, because cross-reactivity
between serotypes occurs in these assays, this finding was
not conclusive
Description
Keywords
Foot-and-Mouth Disease Virus Serotype SAT 3, Long-Horned Ankole Calf
Citation
Dhikusooka, M. T., Tjørnehøj, K., Ayebazibwe, C., Namatovu, A., Ruhweza, S., Siegismund, H. R., ... & Belsham, G. J. (2015). Foot-and-mouth disease virus serotype SAT 3 in long-horned Ankole calf, Uganda. Emerging Infectious Diseases, 21(1), 111. http://dx.doi.org/10.3201/eid2101.140995