Prediction equations for body composition of children and adolescents aged 8e19 years in Uganda using deuterium dilution as the reference technique
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Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
Clinical Nutrition ESPEN
Abstract
Background and aims: Body composition is important as a marker of both current and future health
status. Bioelectrical impedance analysis (BIA) is a simple and accurate method for estimating body
composition in field, clinical and research settings, if standard protocol procedures are followed. However,
BIA requires population-specific equations since applicability of existing equations to diverse
populations has been questioned. This study aimed to derive predictive equations for Total Body Water
(TBW), Fat Free Mass (FFM) and Fat Mass (FM) determinations with BIA and anthropometric measurements
in a population of children and adolescents aged 8e19 years in Uganda.
Methods: A cross-sectional study was conducted among 203 children and adolescents aged 8e19 years
attending schools in Kampala district (also referred to as Kampala city since the city is conterminous
with the district), Uganda through a two-stage cluster sample design. Deuterium dilution method (DDM)
was used as the reference measure while BIA and anthropometric measures were used to create the new
body composition prediction equations through multivariate regression.
Results: The new prediction equations explained 88%, 87% and 71% of the variance in TBW, FFM % and of
FM respectively with no statistical shrinkage upon cross-validation. The linear regression models proposed
in this study were well adjusted with respect to TBW, FFM and FM. Log of TBW obtained by
DDM ¼ 0.0129 Impedance index þ 0.0055 Age þ 0.0049Waist Circumference þ 0.1219Ht2 þ 2.0388.
Log of FFM obtained by DDM ¼ 0.0197 FFM obtained by BIA e 0.0181 sex code e
0.00055 Impedance þ 3.1761. Log of FM obtained by DDM ¼ 0.0634 FM obtained by BIA e 0.1881 sex
code þ 0.0252 Weight þ 0.5273.
Description
Keywords
Body composition Bioelectric, impedance analysis, Deuterium dilution method, Predictive equations Children Adolescents