Ebola Hemorrhagic Fever Associated with Novel Virus Strain, Uganda, 2007–2008

dc.contributor.authorWamala, Joseph F.
dc.contributor.authorLukwago, Luswa
dc.contributor.authorMalimbo, Mugagga
dc.contributor.authorNguku, Patrick
dc.contributor.authorYoti, Zabulon
dc.contributor.authorMusenero, Monica
dc.contributor.authorAmone, Jackson
dc.contributor.authorMbabazi, William
dc.contributor.authorNanyunja, Miriam
dc.contributor.authorZaramba, Sam
dc.contributor.authorOpio, Alex
dc.contributor.authorLutwama, Julius J.
dc.contributor.authorTalisuna, Ambrose O.
dc.contributor.authorOkware, Sam I.
dc.date.accessioned2021-12-15T10:53:36Z
dc.date.available2021-12-15T10:53:36Z
dc.date.issued2010
dc.description.abstractDuring August 2007–February 2008, the novel Bundibugyo ebola virus species was identified during an outbreak of Ebola viral hemorrhagic fever in Bundibugyo district, western Uganda. To characterize the outbreak as a requisite for determining response, we instituted a caseseries investigation. We identified 192 suspected cases, of which 42 (22%) were laboratory positive for the novel species; 74 (38%) were probable, and 77 (40%) were negative. Laboratory confirmation lagged behind outbreak verification by 3 months. Bundibugyo ebola virus was less fatal (case fatality rate 34%) than Ebola viruses that had caused previous outbreaks in the region, and most transmission was associated with handling of dead persons without appropriate protection (adjusted odds ratio 3.83, 95% confidence interval 1.78–8.23). Our study highlights the need for maintaining a high index of suspicion for viral hemorrhagic fevers among healthcare workers, building local capacity for laboratory confirmation of viral hemorrhagic fevers, and institutionalizing standard precautions.en_US
dc.identifier.citationWamala, J. F., Lukwago, L., Malimbo, M., Nguku, P., Yoti, Z., Musenero, M., ... & Okware, S. I. (2010). Ebola hemorrhagic fever associated with novel virus strain, Uganda, 2007–2008. Emerging infectious diseases, 16(7), 1087.en_US
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/pmc3321896/
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/581
dc.language.isoenen_US
dc.publisherEmerging infectious diseasesen_US
dc.subjectEbola Hemorrhagic feveren_US
dc.subjectNovel Virus Strainen_US
dc.titleEbola Hemorrhagic Fever Associated with Novel Virus Strain, Uganda, 2007–2008en_US
dc.typeArticleen_US
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