Systematic Review of the Global Epidemiology of Viral-induced Acute Liver Failure

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Date
2020
Authors
Patterson, Jenna
Silal, Sheetal
Setshedi, Mashiko
Hussey, Gregory D.
Kagina, Benjamin M.
Muloiwa, Rudzani
Journal Title
Journal ISSN
Volume Title
Publisher
BMJ open
Abstract
The aetiology and burden of viral-induced acute liver failure remains unclear globally. It is important to understand the epidemiology of viral-induced ALF to plan for clinical case management and case prevention. Immunisation against hepatitis A and hepatitis B should be prioritised in low-income and middle-income countries to prevent high viral-induced acute liver failure mortality rates, especially in settings where resources for managing acute liver failure are lacking. The expanded use of hepatitis E immunisation should be explored as hepatitis E virus was the most common cause of acute liver failure.
Description
Keywords
aetiology, viral-induced acute liver failure, hepatitis A and hepatitis B
Citation
Patterson, J., Hussey, H. S., Silal, S., Goddard, L., Setshedi, M., Spearman, W., ... & Muloiwa, R. (2020). Systematic review of the global epidemiology of viral-induced acute liver failure. BMJ open, 10(7), e037473.http://dx.doi.org/10.1136/bmjopen-2020-037473