Systematic Review of the Global Epidemiology of Viral-induced Acute Liver Failure

Abstract
The aetiology and burden of viral-induced acute liver failure remains unclear globally. It is important to understand the epidemiology of viral-induced ALF to plan for clinical case management and case prevention. Immunisation against hepatitis A and hepatitis B should be prioritised in low-income and middle-income countries to prevent high viral-induced acute liver failure mortality rates, especially in settings where resources for managing acute liver failure are lacking. The expanded use of hepatitis E immunisation should be explored as hepatitis E virus was the most common cause of acute liver failure.
Description
Keywords
aetiology, viral-induced acute liver failure, hepatitis A and hepatitis B
Citation
Patterson, J., Hussey, H. S., Silal, S., Goddard, L., Setshedi, M., Spearman, W., ... & Muloiwa, R. (2020). Systematic review of the global epidemiology of viral-induced acute liver failure. BMJ open, 10(7), e037473.http://dx.doi.org/10.1136/bmjopen-2020-037473