Breast Cancer Risk Factors among Ugandan Women at a Tertiary Hospital: A Case-Control Study
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Date
2016
Journal Title
Journal ISSN
Volume Title
Publisher
Oncology
Abstract
Although East Africa, like other countries in sub-Saharan Africa, has a lower incidence of breast cancer than high-income countries, the disease rate is rising steeply in Africa; it has nearly tripled in the past few decades in Uganda.
There is a paucity of studies that have examined the relation between reproductive factors and breast cancer risk factors
in Ugandan women. Objective: To determine breast cancer risk factors among indigenous Ugandan women.
Methods: This is a hospital-based unmatched case-control study. Interviews were conducted between 2011 and 2012
using structured questionnaires. Patients with histologyproven breast cancer were recruited over a 2-year period.
Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results: A total of 350
women were recruited; 113 were cases and 237 were controls. The mean age was 47.5 years (SD 14) for the cases and
45.5 years (SD 14.1) for the controls. The odds of breast cancer risk seemed lower for those who breastfed (adjusted
OR = 0.04; 95% CI: 0.01, 0.18). There was no significance for early age at first full-term birth (adjusted OR = 1.96; 95% CI:
0.97, 3.96; p = 0.061), and urban residence carried no increased odds of breast cancer either (p = 0.201). Conclusion:
Breastfeeding seems to be associated with reduced odds of breast cancer
Description
Keywords
Breast cancer risk factors, Ugandan women, Sub-Saharan Africa
Citation
Galukande, M., Wabinga, H., Mirembe, F., Karamagi, C., & Asea, A. (2016). Breast cancer risk factors among Ugandan women at a tertiary hospital: a case-control study. Oncology, 90(6), 356-362.