Assessment Of The Diagnostic Performance Of Truehb Point-Of-Care Hemometer Compared With Sysmex I3 Analyzer Among Patients At International Hospital Kampala, Uganda

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dc.contributor.authorTaremwa, Ivan Mugisha
dc.contributor.authorNdeze, Ivan
dc.contributor.authorMwambi, Bashir
dc.contributor.authorAtuhairwe, Christine
dc.contributor.authorAchieng, Diana Inda
dc.contributor.authorNatukunda, Bernard
dc.date.accessioned2022-01-24T13:51:23Z
dc.date.available2022-01-24T13:51:23Z
dc.date.issued2019
dc.description.abstractTo assess the diagnostic performance of TrueHb® point-of-care (POC) hemometer compared with Sysmex i3 analyzer at International Hospital Kampala, Uganda.We analyzed ethylenediaminetetraacetic acid blood samples to estimate hemoglobin (Hb) levels using parallel testing with TrueHb® hemometer and Sysmex i3 analyzer. Data were analyzed to ascertain the diagnostic performance of the test assays using the Bland and Altman method. Sensitivity, specificity, positive and negative predictive values were calculated.The study enrolled 402 patients; of these, 156 (38.8%) were males. The average Hb levels were 8.7±1.8 and 13.3±2.6 g/dL for the anemic and nonanemic patients, respectively. One hundred and fifty-five participants were anemic, giving anemia prevalence of 38.56% (95% CI: 35.17–40.38). The mean difference of the TrueHb® and Sysmex i3 assays was 2.2219 (SD 1.07915), and the two devices did not show a difference in their measurements (t=−2.407, p-value 0.017, 95% CI: −0.095–0.010). Further, they showed a significant level of agreement (t=41.281; 95% CI: 2.1161–2.3277) and intraclass correlation coefficients (ICC=0.793). The sensitivity, specificity, positive and negative predictive values were 100.00%, 51.01%, 55.16% and 100.00%, respectively. The average performance turnaround time (TAT) for the TrueHb® hemometer was 2.46 mins (95% CI: 2.37–2.55). TrueHb® POC hemometer is an accurate POC for Hb estimation with a good performance agreement with the Sysmex i3 analyzer. This, coupled with its utility aspects, makes it a good diagnostic tool in a high anemia burden and low-resource setting.en_US
dc.identifier.citationTaremwa, I. M., Ndeze, I., Mwambi, B., Atuhairwe, C., Achieng, D. I., & Natukunda, B. (2019). Assessment of the diagnostic performance of TrueHb® point-of-care hemometer compared with Sysmex i3 analyzer among patients at International Hospital Kampala, Uganda. Journal of blood medicine, 10, 85. doi: 10.2147/JBM.S188302en_US
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1495
dc.language.isoenen_US
dc.publisherJournal of blood medicineen_US
dc.subjectanemia, hemoglobin estimation, point-of-care testing, TrueHb®, Sysmex i3, Ugandaen_US
dc.titleAssessment Of The Diagnostic Performance Of Truehb Point-Of-Care Hemometer Compared With Sysmex I3 Analyzer Among Patients At International Hospital Kampala, Ugandaen_US
dc.typeArticleen_US
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