Incidence and Determinants of Perinatal Mortality among Women with Obstructed Labour in Eastern Uganda: A Prospective Cohort Study
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Date
2021-07-15
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Maternal health, neonatology and perinatology
Abstract
In Uganda, the incidence and determinants of perinatal death in obstructed labour are not well
documented. We determined the incidence and determinants of perinatal mortality among women with
obstructed labour in Eastern Uganda.
Between July 2018 and September 2019, 584 with obstructed labour were recruited and followed up to
the 7th day postnatal. Information on maternal characteristics, obstetric factors and laboratory parameters was
collected. Each patient received the standard perioperative care. We used a generalized linear model for the
Poisson family, with a log link and robust variance estimation to determine the association between the exposure
variables and perinatal death.
Of the 623 women diagnosed with obstructed labour, 584 met the eligibility criteria. There were 24 fresh
still births (FSB) and 32 early neonatal deaths (ENND) giving an FSB rate of 43.8 (95% CI 28.3–64.4) deaths per 1000
total births; early neonatal death rate of 58.4 (95% CI 40.3–81.4) deaths per 1000 and an overall perinatal mortality
rate of 102.2 (95% CI 79.4–130.6) deaths in the first 7 days of life. A mother being referred in active labour adjusted
risk ratio of 2.84 (95% CI: 1.35–5.96) and having high blood lactate levels at recruitment adjusted risk ratio 2.71 (95%
CI: 1.26–4.24) were the determinants of perinatal deaths.
The incidence of perinatal death was four times the regional and national average. Babies to women
referred in active labour and those with high maternal blood lactate were more likely to die.
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Citation
Musaba, M.W., Ndeezi, G., Barageine, J.K. et al. Incidence and determinants of perinatal mortality among women with obstructed labour in eastern Uganda: a prospective cohort study. matern health, neonatol and perinatol 7, 13 (2021). https://doi.org/10.1186/s40748-021-00133-7