Use of antibacterials in the management of symptoms of acute respiratory tract infections among children under five years in Gulu, northern Uganda: Prevalence and determinants

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dc.contributor.authorLanyero, Hindum
dc.contributor.authorEriksen, Jaran
dc.contributor.authorObua, Celestino
dc.contributor.authorStålsby Lundborg, Cecilia
dc.contributor.authorNanzigu, Sarah
dc.contributor.authorKatureebe, Agaba
dc.contributor.authorKalyango, Joan N.
dc.contributor.authorOcan, Moses
dc.date.accessioned2022-02-03T21:11:18Z
dc.date.available2022-02-03T21:11:18Z
dc.date.issued2020
dc.description.abstractInappropriate use of antibacterials is a major public health challenge as it can promote emergence of resistance, wastage of financial resources, morbidity and mortality. In this study, we determined the prevalence and factors associated with antibacterial use in managing symptoms of acute respiratory tract infections (ARIs) in households in rural communities of Gulu district, northern Uganda. A cross-sectional study was conducted among households selected using multi-stage sampling. Data were collected through interviews with care-givers of children under five years, using a structured interviewer administered questionnaire. Out of the 856 children who had symptoms of ARIs, 515 (60.2%; CI: 54.5%-65.6%) were treated with antibacterials. The most commonly used antibacterials were amoxicillin (55.2%, n = 358), cotrimoxazole (15.4%, n = 100) and metronidazole (11.4%, n = 74). The determinants of antibacterial use included; getting treatment from a health facility (AOR: 1.85, CI: 1.34–2.56, P < 0.001), households located in peri-urban area (AOR: 2.54, CI: 1.34–4.84, P = 0.005), and a child having cough (AOR: 7.02, CI: 4.36–11.31, P < 0.001). The prevalence of antibacterial use among children under five years with symptoms of ARIs is high in communities of Gulu district, northern Uganda. Getting treatment from a health facility, if a household was located in a peri-urban area and having a cough are positive predictors of antibacterial use. There is need for targeted education on appropriate antibacterial use in rural communities and hospital settings where over prescription is most likely especially in treating symptoms of ARIs among children under five years.en_US
dc.identifier.citationLanyero H, Eriksen J, Obua C, Stålsby Lundborg C, Nanzigu S, Katureebe A, et al. (2020) Use of antibacterials in the management of symptoms of acute respiratory tract infections among children under five years in Gulu, northern Uganda: Prevalence and determinants. PLoS ONE 15(6): e0235164. https://doi.org/10.1371/journal. pone.0235164en_US
dc.identifier.urihttps://doi.org/10.1371/journal. pone.0235164
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1867
dc.language.isoenen_US
dc.publisherPLoS ONEen_US
dc.subjectAntibacterialsen_US
dc.subjectAcute respiratory tract infectionsen_US
dc.subjectChildrenen_US
dc.subjectGuluen_US
dc.titleUse of antibacterials in the management of symptoms of acute respiratory tract infections among children under five years in Gulu, northern Uganda: Prevalence and determinantsen_US
dc.typeArticleen_US
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