Design and execution of a public randomization ceremony to enhance stakeholder engagement within a cluster randomized trial to improve tuberculosis diagnosis in Uganda

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dc.contributor.authorReza, Tania F.
dc.contributor.authorNalugwa, Talemwa
dc.contributor.authorNantale, Mariam
dc.contributor.authorAdams, Katherine
dc.contributor.authorFielding, Katherine
dc.contributor.authorNakaweesa, Annet
dc.contributor.authorOyuku, Denis
dc.contributor.authorNabwire, Sarah
dc.contributor.authorMusinguzi, Johnson
dc.contributor.authorOjok, Christopher
dc.contributor.authorBabirye, Diana
dc.contributor.authorAckerman, Sara L.
dc.contributor.authorHandley, Margaret A.
dc.contributor.authorKityamuwesi, Alex
dc.contributor.authorDowdy, David W.
dc.contributor.authorMoore, David A.J.
dc.contributor.authorDavis, J. Lucian
dc.contributor.authorTuryahabwe, Stavia
dc.contributor.authorKatamba, Achilles
dc.contributor.authorCattamanch, Adithya
dc.date.accessioned2023-01-17T20:23:41Z
dc.date.available2023-01-17T20:23:41Z
dc.date.issued2021
dc.description.abstractPublic randomization ceremonies have been proposed as a strategy to strengthen stakeholder engagement and address concerns and misconceptions associated with trial randomization. However, there are few published examples that describe how to conduct a public randomization ceremony with meaningful stakeholder engagement or how such ceremonies impact stakeholder perceptions about randomization and the randomization process. Cluster randomization for the GeneXpert Performance Evaluation for Linkage to Tuberculosis Care (XPEL-TB) trial was conducted at a public randomization ceremony attended by 70 stakeholders in Kampala, Uganda. Presentations given by the Acting Assistant Commissioner from the Uganda National Tuberculosis and Leprosy Programme and trial investigators emphasized how the trial aimed to further national TB goals, as well as how stakeholders contributed to the intervention design. The purpose and process of randomization were described using simple text and visuals. Randomization was an interactive activity that required participation of stakeholders from each trial site. A survey administered to stakeholders at the end of the ceremony suggested high comprehension of randomization (98%), trust in the randomization process (96%), and satisfaction with randomization outcomes (96%). Public randomization ceremonies should be considered more routinely to engage stakeholders in and address potential concerns about the fairness and impartiality of the randomization process for community-based trials.en_US
dc.identifier.citationReza, T. F., Nalugwa, T., Nantale, M., Adams, K., Fielding, K., Nakaweesa, A., ... & Cattamanchi, A. (2021). Design and execution of a public randomization ceremony to enhance stakeholder engagement within a cluster randomized trial to improve tuberculosis diagnosis in Uganda. Contemporary clinical trials communications, 22, 100707. https://doi.org/10.1016/j.conctc.2021.100707en_US
dc.identifier.urihttps://doi.org/10.1016/j.conctc.2021.100707
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7003
dc.language.isoenen_US
dc.publisherContemporary clinical trials communicationsen_US
dc.subjectPublic randomization ceremonyen_US
dc.subjectCluster randomized trialsen_US
dc.subjectTrial ethicsen_US
dc.subjectStakeholder engagementen_US
dc.subjectTuberculosisen_US
dc.titleDesign and execution of a public randomization ceremony to enhance stakeholder engagement within a cluster randomized trial to improve tuberculosis diagnosis in Ugandaen_US
dc.typeArticleen_US
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