Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomized-controlled trial results

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dc.contributor.authorMpairwe, Harriet
dc.contributor.authorWebb, Emily L.
dc.contributor.authorMuhangi, Lawrence
dc.contributor.authorNdibazza, Juliet
dc.contributor.authorAkishule, Denise
dc.contributor.authorNampijja, Margaret
dc.contributor.authorNgom-wegi, Sophy
dc.contributor.authorTumusime, Josephine
dc.contributor.authorJones, Frances M.
dc.contributor.authorFitzsimmons, Colin
dc.contributor.authorDunne, David W.
dc.contributor.authorMuwanga, Moses
dc.contributor.authorRodrigues, Laura C.
dc.contributor.authorElliott, Alison M.
dc.date.accessioned2022-01-30T14:54:30Z
dc.date.available2022-01-30T14:54:30Z
dc.date.issued2011
dc.description.abstractAllergy is commoner in developed than in developing countries. Chronic worm infections show inverse associations with allergy, and prenatal exposures may be critical to allergy risk. To determine whether anthelminthic treatment during pregnancy increases the risk of allergy in infancy. A randomized, double-blind, placebo-controlled trial on treatment in pregnancy with albendazole versus placebo and praziquantel versus placebo was conducted in Uganda, with a 2 · 2 factorial design; 2507 women were enrolled; infants’ allergy events were recorded prospectively. The main outcome was doctor-diagnosed infantile eczema.en_US
dc.identifier.citationMpairwe H, Webb EL, Muhangi L, Ndibazza J, Akishule D, Nampijja M, Ngom-wegi S, Tumusime J, Jones FM, Fitzsimmons C, Dunne DW, Muwanga M, Rodrigues LC, Elliott AM. Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomised-controlled trial results. Pediatr Allergy Immunol 2011; 22: 305–312. DOI:10.1111/j.1399-3038.2010.01122.xen_US
dc.identifier.other10.1111/j.1399-3038.2010.01122.x
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1625
dc.language.isoenen_US
dc.publisherPediatric Allergy and Immunologyen_US
dc.subjectAlbendazoleen_US
dc.subjectPraziquantelen_US
dc.subjectWormsen_US
dc.subjectInfantile eczemaen_US
dc.subjectPregnancyen_US
dc.subjectClinical trialsen_US
dc.titleAnthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomized-controlled trial resultsen_US
dc.typeArticleen_US
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