Alcohol Use and HIV Disease Progression in an Antiretroviral Naïve Cohort

Simple item page
dc.contributor.authorHahn, Judith A.
dc.contributor.authorCheng, Debbie M.
dc.contributor.authorEmenyonu, Nneka I.
dc.contributor.authorLloyd-Travaglini, Christine
dc.contributor.authorFatch, Robin
dc.contributor.authorShade, Starley B.
dc.contributor.authorNgabirano, Christine
dc.contributor.authorAdong, Julian
dc.contributor.authorBryant, Kendall
dc.contributor.authorMuyindike, Winnie R.
dc.contributor.authorSamet, Jeffrey H.
dc.date.accessioned2022-01-30T19:31:05Z
dc.date.available2022-01-30T19:31:05Z
dc.date.issued2018
dc.description.abstractAlcohol use has been shown to accelerate disease progression in experimental studies of simian immunodeficiency virus in macaques, but the results in observational studies of HIV have been conflicting. We conducted a prospective cohort study of the impact of unhealthy alcohol use on CD4 cell count among HIV-infected persons in southwestern Uganda not yet eligible for antiretroviral treatment (ART). Unhealthy alcohol consumption was 3-month Alcohol Use Disorders Identification Test – Consumption (AUDIT-C) positive (≥3 for women, ≥4 for men) and/or phosphatidylethanol (PEth - an alcohol biomarker) ≥50 ng/ml, modeled as a time-dependent variable in a linear mixed effects model of CD4 count.en_US
dc.identifier.citationHahn, J. A., Cheng, D. M., Emenyonu, N. I., Lloyd-Travaglini, C., Fatch, R., Shade, S. B., ... & Samet, J. H. (2018). Alcohol use and HIV disease progression in an antiretroviral naive cohort. Journal of acquired immune deficiency syndromes (1999), 77(5), 492. doi:10.1097/QAI.0000000000001624.en_US
dc.identifier.other10.1097/QAI.0000000000001624.
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1634
dc.language.isoenen_US
dc.publisherJournal of acquired immune deficiency syndromesen_US
dc.subjectHIV progressionen_US
dc.subjectPhosphatidylethanolen_US
dc.subjectSub-Saharan Africaen_US
dc.subjectAntiretroviral adherenceen_US
dc.titleAlcohol Use and HIV Disease Progression in an Antiretroviral Naïve Cohorten_US
dc.typeArticleen_US
Files
Collections
Medical and Health Sciences