Ethnomedical uses, chemical constituents, and evidence-based pharmacological properties of Chenopodium ambrosioides L.: extensive overview
Loading...
Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Future Journal of Pharmaceutical Sciences
Abstract
The Chenopodium genus is a plant family widely spread worldwide that includes various plant species reputed to possess several medicinal virtues in folk medicines. Chenopodium ambrosioides L. is among the most used plants in traditional medicines worldwide. This review aimed to highlight ethnomedicinal uses, phytochemical status, and pharmacological properties of C. ambrosioides L. Main body of the abstract: The analysis of relevant data highlights various ethnomedicinal uses against human
and veterinary diseases in forty countries. Most indications consisted of gastrointestinal tract dysfunctioning troubles
and worms parasitemia. Around 330 chemical compounds have been identified in different plant parts, especially in
its essential oil fractions (59.84%). However, only a few compounds—mainly monoterpenes and glycosides—have
been isolated and characterized. Experimental pharmacological studies validated a large scale of significant health
benefits. It appeared that many monoterpenes are antioxidant, insecticidal, trypanocidal, analgesic, antifungal, antiinflammatory,
anti-arthritic, acaricidal, amoebicidal, anthelmintic, anticancer, antibacterial, antidiabetic, antidiarrheal, antifertility, antifungal, anti-leishmanial, antimalarial, antipyretic, antisickling, antischistosomal, antiulcer, anxiolytic, immunomodulatory, molluscicidal, and vasorelaxant agents. Short conclusion: Thus, the Chenopodium ambrosioides species necessitates further chemical studies to isolate and new bioactive secondary metabolites and pharmacological investigations to precise the mechanisms of action before clinical trials.
Description
Keywords
Chenopodium ambrosioides, Bioactive compound, Therapeutic indications, Pharmacological bioactivity
Citation
Kasali, F. M., Tusiimire, J., Kadima, J. N., & Agaba, A. G. (2021). Ethnomedical uses, chemical constituents, and evidence-based pharmacological properties of Chenopodium ambrosioides L.: extensive overview. Future Journal of Pharmaceutical Sciences, 7(1), 1-36.