Effect of intermittent preventive treatment for malaria with dihydroartemisinin-piperaquine on immune responses to vaccines among rural Ugandan adolescents: randomised controlled trial protocol B for the ‘POPulation differences in VACcine responses’ (POPVAC) programme
| dc.contributor.author | Natukunda, Agnes | |
| dc.contributor.author | Nkurunungi, Gyaviira | |
| dc.contributor.author | Oduru, Gloria | |
| dc.contributor.author | Kabuubi, Prossy N. | |
| dc.contributor.author | Mutebe, Alex | |
| dc.date.accessioned | 2025-06-24T09:14:07Z | |
| dc.date.available | 2025-06-24T09:14:07Z | |
| dc.date.issued | 2020-02-16 | |
| dc.description.abstract | Drivers of lower vaccine efficacy and impaired vaccine-specific immune responses in low-income versus high-income countries, and in rural compared with urban settings, are not fully elucidated. Repeated exposure to and immunomodulation by parasite infections may be important. We focus on Plasmodium falciparum malaria, aiming to determine whether there are reversible effects of malaria infection on vaccine responses. | |
| dc.identifier.citation | Natukunda, A., Nkurunungi, G., Zirimenya, L., Nassuuna, J., Oduru, G., Amongin, R., ... & Elliott, A. M. (2020). Effect of intermittent preventive treatment for malaria with dihydroartemisinin-piperaquine on immune responses to vaccines among rural Ugandan adolescents: randomised controlled trial protocol B for the ‘POPulation differences in VACcine responses’(POPVAC) programme. BMJ open, 11(2), e040427. | |
| dc.identifier.other | https://doi.org/10.1136/bmjopen-2020-040427 | |
| dc.identifier.uri | https://nru.uncst.go.ug/handle/123456789/11894 | |
| dc.language.iso | en | |
| dc.publisher | BMJ open | |
| dc.title | Effect of intermittent preventive treatment for malaria with dihydroartemisinin-piperaquine on immune responses to vaccines among rural Ugandan adolescents: randomised controlled trial protocol B for the ‘POPulation differences in VACcine responses’ (POPVAC) programme | |
| dc.type | Article |