Pharyngeal carriage of Neisseria meningitidis in 2–19-year-old individuals in Uganda

dc.contributor.authorCaugant, Dominique A.
dc.contributor.authorFogg, Carole
dc.contributor.authorBajunirwe, Francis
dc.contributor.authorPiola, Patrice
dc.contributor.authorTwesigye, Rogers
dc.contributor.authorMutebi, Fred
dc.contributor.authorFrøholm, L. Oddvar
dc.contributor.authorRosenqvist, Einar
dc.contributor.authorBatwala, Vincent
dc.contributor.authorAaberge, Ingeborg S.
dc.contributor.authorRottingen, John-Arne
dc.contributor.authorGuerin, Philippe J.
dc.date.accessioned2021-12-15T20:35:53Z
dc.date.available2021-12-15T20:35:53Z
dc.date.issued2006
dc.description.abstractIn southern Uganda, only sporadic cases of serogroup A meningococcal disease have been reported since 2000. As part of an immunogenicity study of the tetravalent meningococcal polysaccharide vaccine, nasopharyngeal swab samples were collected twice, 4 weeks apart, from 2–19-year-old healthy individuals in Mbarara, Uganda. Only 15 (2.0%) of the 750 individuals carried meningococci asymptomatically. Most of the strains were non-serogroupable and none were serogroup A. However, two individuals carried a serogroup W135 strain, sequence type (ST)-11, similar to the clone that was responsible for the epidemic in Burkina Faso in 2002. Our study further demonstrates the geographical spread of serogroup W135 ST-11 strain and thus the potential epidemic risk.en_US
dc.identifier.citationCaugant, D. A., Fogg, C., Bajunirwe, F., Piola, P., Twesigye, R., Mutebi, F., ... & Guerin, P. J. (2006). Pharyngeal carriage of Neisseria meningitidis in 2–19-year-old individuals in Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene, 100(12), 1159-1163. https://doi.org/10.1016/j.trstmh.2006.01.004en_US
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/670
dc.language.isoenen_US
dc.publisherTransactions of The Royal Society of Tropical Medicine and Hygieneen_US
dc.subjectNeisseria meningitidis, Meningococcal carriage, Serogroup W135, Ugandaen_US
dc.titlePharyngeal carriage of Neisseria meningitidis in 2–19-year-old individuals in Ugandaen_US
dc.typeArticleen_US
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