Risk factors for Burkitt lymphoma in children in East Africa
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Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
Research Square
Abstract
Endemic Burkitt lymphoma (eBL), a malignancy of immune B cells, is the most common childhood
cancer in sub-Saharan Africa eBL is curable when it's identified early, but it's rapidly fatal without
treatment Children in sub-Saharan Africa are over 50 times more likely to develop eBL than children living
anywhere else in the world Unfortunately, few studies have examined the risk factors associated with eBL
To address that gap, researchers conducted a study of eBL in children in three countries in East Africa
They analyzed the relationship between eBL and infections, environmental, and genetic risk factors and
focused their conclusions on results observed in at least two countries to minimize false-positives Risk of
eBL was associated with low socio-economic status inpatient malaria treatment and living in areas
targeted for malaria suppression In addition to exploring eBL risk factors, this study also demonstrates
the potential to study cancer risk in East Africa and to detect, treat, or prevent eBL Learn more at
emblem.cancer.gov Peprah et al. Risk factors for Burkitt lymphoma in East African children and minors.
Int. J. Cancer. (2019)
Description
Keywords
Cancer, Epidemiology, Burkitt lymphoma, Endemic burkitt lymphoma, Lymphoma, Sub-Saharan Africa, East Africa, Uganda
Citation
Peprah, S., Ogwang, M. D., Kerchan, P., Reynolds, S. J., Tenge, C. N., Were, P. A., ... & Mbulaiteye, S. M. (2019). Risk factors for Burkitt lymphoma in children in East Africa. https://doi.org/10.21203/rs.2.15122/v1