Maternal HIV infection and other factors associated with growth outcomes of HIV-uninfected infants in Entebbe, Uganda

Simple item page
dc.contributor.authorMuhangi, Lawrence
dc.contributor.authorLule, Swaib A.
dc.contributor.authorMpairwe, Harriet
dc.contributor.authorNdibazza, Juliet
dc.contributor.authorKizza, Moses
dc.contributor.authorNampijja, Margaret
dc.contributor.authorNakazibwe, Esther
dc.contributor.authorKihembo, Macklyn
dc.contributor.authorElliott, Alison M.
dc.contributor.authorWebb, Emily L.
dc.date.accessioned2022-01-30T14:28:44Z
dc.date.available2022-01-30T14:28:44Z
dc.date.issued2013
dc.description.abstractTo assess the associations between maternal HIV infection and growth outcomes of HIV-exposed but uninfected infants and to identify other predictors for poor growth among this population. Within a trial of de-worming during pregnancy, the cohort of offspring was followed from birth. HIV status of the mothers and their children was investigated and growth data for children were obtained at age 1 year. Lengthfor- age, weight-for-age and weight-for-length Z-scores were calculated for each child; Z-scores ,22 were defined as stunting, underweight and wasting, respectively. Setting: The study was conducted in Entebbe municipality and Katabi subcounty, Uganda. Subjects: The sample consisted of 1502 children aged 1 year: HIV-unexposed (n 1380) and HIV-exposed not infected (n 122). Results: Prevalence of stunting, underweight and wasting was 14?2%, 8?0% and3?9%, respectively. There was evidence for an association between maternal HIV infection and odds of being underweight (adjusted OR52?32; 95% CI 1?32, 4?09; P50?006) but no evidence for an association with stunting or with wasting. Young maternal age, low maternal education, low birth weight, early weaning and experiencing a higher number of episodes of malaria during infancy were independent predictors for stunting and underweight. A higher number of living children in the family was associated with wasting. Conclusions: Maternal HIV infection was associated with being underweight in HIV-exposed uninfected infants. The success of programmes for prevention of mother-to-child HIV transmission means that an increasing number of infants will be born to HIV-infected women without acquiring HIV. Therefore, viable nutritional interventions need to be identified for this population.en_US
dc.identifier.citationMuhangi, L., Lule, S. A., Mpairwe, H., Ndibazza, J., Kizza, M., Nampijja, M., ... & Webb, E. L. (2013). Maternal HIV infection and other factors associated with growth outcomes of HIV-uninfected infants in Entebbe, Uganda. Public health nutrition, 16(9), 1548-1557. doi:10.1017/S1368980013000499en_US
dc.identifier.other10.1017/S1368980013000499
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1622
dc.language.isoenen_US
dc.publisherPublic health nutritionen_US
dc.subjectMaternal HIV infectionen_US
dc.subjectGrowth outcomesen_US
dc.subjectHIV-uninfected infantsen_US
dc.subjectUgandaen_US
dc.titleMaternal HIV infection and other factors associated with growth outcomes of HIV-uninfected infants in Entebbe, Ugandaen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
maternal-hiv-infection-and-other-factors-associated-with-growth-outcomes-of-hiv-uninfected-infants-in-entebbe-uganda.pdf
Size:
153.51 KB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medical and Health Sciences