Factors That Affect Quality of Life among People Living with HIV Attending an Urban Clinic in Uganda: A Cohort Study

dc.contributor.authorMutabazi-Mwesigire, Doris
dc.contributor.authorKatamba, Achilles
dc.contributor.authorMartin, Faith
dc.contributor.authorSeeley, Janet
dc.contributor.authorWu, Albert W.
dc.date.accessioned2021-12-20T18:27:38Z
dc.date.available2021-12-20T18:27:38Z
dc.date.issued2015
dc.description.abstractIntroduction With the availability of antiretroviral therapy (ART) and primary general care for people living with HIV (PLHIV) in resource limited settings, PLHIV are living longer, and HIV has been transformed into a chronic illness. People are diagnosed and started on treatment when they are relatively well. Although ART results in clinical improvement, the ultimate goal of treatment is full physical functioning and general well-being, with a focus on quality of life rather than clinical outcomes. However, there has been little research on the relationship of specific factors to quality of life in PLHIV. The objective of this study was to investigate factors associated with quality of life among PLHIV in Uganda receiving basic care and those on ART. Methods We enrolled 1274 patients attending an HIV outpatient clinic into a prospective cohort study. Of these, 640 received ART. All were followed up at 3 and 6 months. Health related quality of life was assessed with the MOS-HIV Health Survey and the Global Person Generated Index (GPGI). Multivariate linear regression and logistic regression with generalized estimating equations were used to examine the relationship of social behavioral and disease factors with Physical Health Summary (PHS) score, Mental Health Summary (MHS) score, and GPGI. Results Among PLHIV receiving basic care, PHS was associated with: sex (p=0.045) - females had lower PHS; age in years at enrollment (p=0.0001) - older patients had lower PHS; and depression (pen_US
dc.identifier.citationMutabazi-Mwesigire, D., Katamba, A., Martin, F., Seeley, J., & Wu, A. W. (2015). Factors that affect quality of life among people living with HIV attending an urban clinic in Uganda: a cohort study. PloS one, 10(6), e0126810. DOI: https://doi.org/10.1371/journal.pone.0126810en_US
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0126810
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0126810
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/860
dc.language.isoenen_US
dc.publisherPloS oneen_US
dc.relation.ispartofseriesPloS one;
dc.subjectHIVen_US
dc.subjectUrban Clinicen_US
dc.subjectUgandaen_US
dc.titleFactors That Affect Quality of Life among People Living with HIV Attending an Urban Clinic in Uganda: A Cohort Studyen_US
dc.typeArticleen_US
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