Is distance associated with tuberculosis treatment outcomes? A retrospective cohort study in Kampala, Uganda

Simple item page
dc.contributor.authorRobsky, Katherine O.
dc.contributor.authorHughes, Seamus
dc.contributor.authorKityamuwesi, Alex
dc.contributor.authorKendall, Emily A.
dc.contributor.authorKitonsa, Peter James
dc.contributor.authorDowdy, David W.
dc.contributor.authorKatamba, Achilles
dc.date.accessioned2023-01-18T18:07:37Z
dc.date.available2023-01-18T18:07:37Z
dc.date.issued2020
dc.description.abstractChallenges accessing nearby health facilities may be a barrier to initiating and completing tuberculosis (TB) treatment. We aimed to evaluate whether distance from residence to health facility chosen for treatment is associated with TB treatment outcomes. Methods: We conducted a retrospective cohort study of all patients initiating TB treatment at six health facilities in Kampala from 2014 to 2016. We investigated associations between distance to treating facility and unfavorable TB treatment outcomes (death, loss to follow up, or treatment failure) using multivariable Poisson regression. Results: Unfavorable treatment outcomes occurred in 20% (339/1691) of TB patients. The adjusted relative risk (aRR) for unfavorable treatment outcomes (compared to treatment success) was 0.87 (95% confidence interval [CI] 0.70, 1.07) for patients living ≥2 km from the facility compared to those living closer. When we separately compared each type of unfavorable treatment outcome to favorable outcomes, those living ≥2 km from the facility had increased risk of death (aRR 1.42 [95%CI 0.99, 2.03]) but decreased risk for loss to follow-up (aRR 0.57 [95%CI 0.41, 0.78]) than those living within 2 km. Conclusions: Distance from home residence to TB treatment facility is associated with increased risk of death but decreased risk of loss to follow up. Those who seek care further from home may have advanced disease, but once enrolled may be more likely to remain in treatment.en_US
dc.identifier.citationRobsky, K. O., Hughes, S., Kityamuwesi, A., Kendall, E. A., Kitonsa, P. J., Dowdy, D. W., & Katamba, A. (2020). Is distance associated with tuberculosis treatment outcomes? A retrospective cohort study in Kampala, Uganda. BMC infectious diseases, 20(1), 1-9. https://doi.org/10.1186/s12879-020-05099-zen_US
dc.identifier.urihttps://doi.org/10.1186/s12879-020-05099-z
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7052
dc.language.isoenen_US
dc.publisherBMC infectious diseasesen_US
dc.subjectEpidemiologyen_US
dc.subjectHealth systems researchen_US
dc.subjectGeographic information systemsen_US
dc.titleIs distance associated with tuberculosis treatment outcomes? A retrospective cohort study in Kampala, Ugandaen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Is distance associated with tuberculosis.pdf
Size:
1.77 MB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medical and Health Sciences