Target, Suspect and Non-Target Screening of Silylated Derivatives of Polar Compounds Based on Single Ion Monitoring GC-MS
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Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
International journal of environmental research and public health
Abstract
There is growing interest in determining the unidentified peaks within a sample spectra
besides the analytes of interest. Availability of reference standards and hyphenated instruments has
been a key and limiting factor in the rapid determination of emerging pollutants in the environment. In
this work, polar compounds were silylated and analyzed with gas chromatography mass spectrometry
(GC-MS) to determine the abundant fragments within the single ion monitoring (SIM) mode and
methodology. Detection limits and recoveries of the compounds were established in river water,
wastewater, biosolid and sediment matrices. Then, specific types of polar compounds that are
classified as emerging contaminants, pharmaceuticals and personal care products, in the environment
were targeted in the Mgeni and Msunduzi Rivers. We also performed suspect and non-target analysis
screening to identify several other polar compounds in these rivers. A total of 12 compounds were
quantified out of approximately 50 detected emerging contaminants in the Mgeni and Msunduzi
Rivers. This study is significant for Africa, where the studies of emerging contaminants are limited
and not usually prioritized.
Description
Keywords
Suspect and non-target analysis, GC-MS, Emerging pollutants, Pharmaceutical and personal care products
Citation
Gumbi, B. P., Moodley, B., Birungi, G., & Ndungu, P. G. (2019). Target, suspect and non-target screening of silylated derivatives of polar compounds based on single Ion monitoring GC-MS. International journal of environmental research and public health, 16(20), 4022. doi:10.3390/ijerph16204022