Safety of Licensed Vaccines in HIV-Infected Persons: A Systematic Review Protocol
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Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
Systematic reviews
Abstract
Safety of vaccines remains a cornerstone of building public trust on the use of these cost-effective and life-saving public health interventions. In some settings, particularly Sub-Saharan Africa, there is a high prevalence of HIV infection and a high burden of vaccine-preventable diseases. There is evidence suggesting that the immunity induced by some commonly used vaccines is not durable in HIV-infected persons, and therefore, repeated vaccination may be considered to ensure optimal vaccine-induced immunity in this population. However, some vaccines, particularly the live vaccines, may be unsafe in HIV-infected persons. There is lack of evidence on the safety profile of commonly used vaccines among HIV-infected persons. We are therefore conducting a systematic review to assess the safety profile of routine vaccines administered to HIV-infected persons.
Description
Keywords
Measle, Pertussis, Herpes Zoster, Rabies, Measle Vaccine
Citation
Kagina, B. M., Wiysonge, C. S., Lesosky, M., Madhi, S. A., & Hussey, G. D. (2014). Safety of licensed vaccines in HIV-infected persons: a systematic review protocol. Systematic reviews, 3(1), 1-6.https://doi.org/10.1186/2046-4053-3-101