High Mortality Associated with Retreatment of Tuberculosis in a Clinic in Kampala, Uganda: A Retrospective Study

The World Health Organization recommends for tuberculosis retreatment a regimen of isoniazid (H), rifampicin (R), ethambutol (E), pyrazinamide (Z), and streptomycin (S) for 2 months, followed by H, R, E, and Z for 1 month and H, R, and E for 5 months. Using data from the National Tuberculosis and Leprosy Program registry, this study determined the long-term outcome under programmatic conditions of patients who were prescribed the retreatment regimen in Kampala, Uganda, between 1997 and 2003. Patients were traced to determine their vital status; 62% (234/377) patients were found dead. Having £ 2 treatment courses and not completing retreatment were associated with mortality in adjusted analyses.

Keywords

High Mortality, Tuberculosis, Clinic, Uganda

Citation

Acuña-Villaorduña, C., Ayakaka, I., Dryden-Peterson, S., Nakubulwa, S., Worodria, W., Reilly, N., ... & Jones-López, EC (2015). High mortality associated with retreatment of tuberculosis in a clinic in Kampala, Uganda: a retrospective study. The American Journal of Tropical Medicine and Hygiene , doi:10.4269/ajtmh.14-0810

URI

https://nru.uncst.go.ug/handle/123456789/3241

Collections

Natural Sciences

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