Clinical outcomes of children with acute asthma and pneumonia in Mulago hospital, Uganda: a prospective study

dc.contributor.authorNantanda, Rebecca
dc.contributor.authorOstergaard, Marianne S
dc.contributor.authorNdeezi, Grace
dc.contributor.authorTumwine, James K
dc.date.accessioned2021-12-09T15:49:32Z
dc.date.available2021-12-09T15:49:32Z
dc.date.issued2014
dc.description.abstractLittle attention has been paid to asthma in ‘under-fives’ in Sub-Saharan Africa. In ‘under-fives’, acute asthma and pneumonia have similar clinical presentation and most children with acute respiratory symptoms are diagnosed with pneumonia according to the WHO criteria. The mortality associated with acute respiratory diseases in Uganda is high but improving, dropping from 24% in 2004 to 11.9% in 2012. We describe the immediate clinical outcomes of children with acute asthma and pneumonia and document the factors associated with prolonged hospitalization and mortality. Methods: We enrolled 614 children aged 2 to 59 months with acute respiratory symptoms presenting at the emergency paediatric unit of Mulago hospital. Clinical histories, physical examination, blood and radiological tests were done. Children with asthma and bronchiolitis were collectively referred to as ‘Asthma syndrome’. Hospitalized children were monitored every 12 hours for a maximum of 7 days. Survival analysis was done to compare outcome of children with asthma and pneumonia. Cox regression analysis was done to determine factors associated with prolonged hospitalization and mortality.en_US
dc.identifier.citationNantanda, R., Ostergaard, M.S., Ndeezi, G. et al. Clinical outcomes of children with acute asthma and pneumonia in Mulago hospital, Uganda: a prospective study. BMC Pediatr 14, 285 (2014). https://doi.org/10.1186/s12887-014-0285-4en_US
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/234
dc.language.isoenen_US
dc.publisherBMC Pediatricsen_US
dc.subjectAsthma, Pneumonia, ‘Under-fives’, Duration of hospitalization, Mortalityen_US
dc.titleClinical outcomes of children with acute asthma and pneumonia in Mulago hospital, Uganda: a prospective studyen_US
dc.typeArticleen_US
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