Reagent Strips as an Aid to Diagnosis of Neonatal Meningitis in a Resource-limited Setting

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dc.contributor.authorBurgoine, Kathy
dc.contributor.authorIkiror, Juliet
dc.contributor.authorNaizuli, Ketty
dc.contributor.authorAchom, Linda
dc.contributor.authorAkol, Sylivia
dc.contributor.authorOlupot-Olupot, Peter
dc.date.accessioned2022-12-27T18:33:40Z
dc.date.available2022-12-27T18:33:40Z
dc.date.issued2019
dc.description.abstractWithout early recognition and treatment, neonatal meningitis (NM) has a high mortality and morbidity. Although some neonates have features of NM, many do not. In many low-resource settings, the laboratory support to diagnose NM is not available, and bedside diagnostics are needed. Methods: This retrospective study was conducted in a neonatal unit in Uganda. Clear cerebrospinal fluid samples were routinely screened for glucose, protein and leukocytes on a ComburVR -10 urinalysis reagent strip. A definitive diagnosis was made using laboratory analysis. The results of the screening and definitive tests were compared. Results: The reagent strip showed moderate sensitivity and high specificity for leukocytes 10 106 cells/l, high sensitivity for protein 100 mg/dl and high specificity for glucose<50 mg/dl. Conclusion: The use of reagent strips has the potential to improve and hasten the diagnosis of probable NM in settings where adequate or timely laboratory support is not available.en_US
dc.identifier.citationBurgoine, K., Ikiror, J., Naizuli, K., Achom, L., Akol, S., & Olupot-Olupot, P. (2019). Reagent strips as an aid to diagnosis of neonatal meningitis in a resource-limited setting. Journal of tropical pediatrics, 65(1), 9-13. doi: 10.1093/tropej/fmy003en_US
dc.identifier.other10.1093/tropej/fmy003
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/6663
dc.language.isoenen_US
dc.publisherJournal of tropical pediatricsen_US
dc.subjectChild healthen_US
dc.subjectPaediatricsen_US
dc.subjectNeonatal sepsisen_US
dc.subjectMeningitisen_US
dc.titleReagent Strips as an Aid to Diagnosis of Neonatal Meningitis in a Resource-limited Settingen_US
dc.typeArticleen_US
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