Video directly observed therapy for supporting and monitoring adherence to tuberculosis treatment in Uganda: a pilot cohort study

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dc.contributor.authorSekandi, Juliet N.
dc.contributor.authorBuregyeya, Esther
dc.contributor.authorZalwango, Sarah
dc.contributor.authorDobbin, Kevin K.
dc.contributor.authorAtuyambe, Lynn
dc.contributor.authorNakkonde, Damalie
dc.contributor.authorTurinawe, Julius
dc.contributor.authorTucker, Emma G.
dc.contributor.authorOlowookere, Shade
dc.contributor.authorTuryahabwe, Stavia
dc.contributor.authorGarfein, Richard S.
dc.date.accessioned2021-12-09T13:28:25Z
dc.date.available2021-12-09T13:28:25Z
dc.date.issued2020
dc.description.abstractIntroduction: Nonadherence to treatment remains an obstacle to tuberculosis (TB) control worldwide. The aim of this study was to evaluate the feasibility of using video directly observed therapy (VDOT) for supporting TB treatment adherence in Uganda. Methods: From May to December 2018, we conducted a pilot cohort study at a TB clinic in Kampala City. We enrolled patients aged 18–65 years with ⩾3 months remaining of their TB treatment. Participants were trained to use a smartphone app to record videos of medication intake and submit them to a secured system. Trained health workers logged into the system to watch the submitted videos. The primary outcome was adherence measured as the fraction of expected doses observed (FEDO). In a secondary analysis, we examined differences in FEDO by sex, age, phone ownership, duration of follow-up, reasons for missed videos and patients’ satisfaction at study exit. Results: Of 52 patients enrolled, 50 were analysed. 28 (56%) were male, the mean age was 31 years (range 19–50 years) and 35 (70%) owned smartphones. Of the 5150 videos expected, 4231 (82.2%) were received. The median FEDO was 85% (interquartile range 66%–94%) and this significantly differed by follow-up duration. Phone malfunction, uncharged battery and VDOT app malfunctions were the commonest reasons for missed videos. 92% of patients reported being very satisfied with using VDOT. Conclusion: VDOT was feasible and acceptable for monitoring and supporting TB treatment. It resulted in high levels of adherence, suggesting that digital technology holds promise in improving patient monitoring in Uganda.en_US
dc.identifier.citationCite this article as: Sekandi JN, Buregyeya E, Zalwango S, et al. Video directly observed therapy for supporting and monitoring adherence to tuberculosis treatment in Uganda: a pilot cohort study. ERJ Open Res 2020; 6: 00175-2019 [https://doi.org/10.1183/23120541.00175-2019].en_US
dc.identifier.uri[https://doi.org/10.1183/23120541.00175-2019].
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/226
dc.language.isoenen_US
dc.publisherERSpublicationsen_US
dc.subjecttuberculosis treatmenten_US
dc.subjectUgandaen_US
dc.subjectVideo directlyen_US
dc.subjecttreatmenten_US
dc.titleVideo directly observed therapy for supporting and monitoring adherence to tuberculosis treatment in Uganda: a pilot cohort studyen_US
dc.typeArticleen_US
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