Detection of Entebbe Bat Virus after 54 Years

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dc.contributor.authorKading, Rebekah C.
dc.contributor.authorKityo, Robert
dc.contributor.authorNakayiki, Teddie
dc.contributor.authorLedermann, Jeremy
dc.contributor.authorCrabtree, Mary B.
dc.contributor.authorLutwama, Julius
dc.contributor.authorMiller, Barry R.
dc.date.accessioned2022-09-09T11:14:47Z
dc.date.available2022-09-09T11:14:47Z
dc.date.issued2015
dc.description.abstractEntebbe bat virus (ENTV; Flaviviridae: Flavivirus), closely related to yellow fever virus, was first isolated from a little free-tailed bat (Chaerephon pumilus) in Uganda in 1957, but was not detected after that initial isolation. In 2011, we isolated ENTV from a little free-tailed bat captured from the attic of a house near where it had originally been found. Infectious virus was recovered from the spleen and lung, and the viral RNA was sequenced and compared with that of the original isolate. Across the polypeptide sequence, there were 76 amino acid substitutions, resulting in 97.8% identity at the amino acid level between the 1957 and 2011 isolates. Further study of this virus would provide valuable insights into the ecological and genetic factors governing the evolution and transmission of bat- and mosquitoborne flaviviruses.en_US
dc.identifier.citationKading, R. C., Kityo, R., Nakayiki, T., Ledermann, J., Crabtree, M. B., Lutwama, J., & Miller, B. R. (2015). Detection of Entebbe bat virus after 54 years. The American journal of tropical medicine and hygiene, 93(3), 475. doi:10.4269/ajtmh.15-0065en_US
dc.identifier.other10.4269/ajtmh.15-0065
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/4650
dc.language.isoenen_US
dc.publisherThe American journal of tropical medicine and hygieneen_US
dc.subjectEntebbeen_US
dc.subjectBat Virusen_US
dc.titleDetection of Entebbe Bat Virus after 54 Yearsen_US
dc.typeArticleen_US
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