Tuberculosis treatment default among HIV-TB co-infected patients in urban Uganda

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dc.contributor.authorElbireer, Sawsan
dc.contributor.authorGuwatudde, David
dc.contributor.authorMudiope, Peter
dc.contributor.authorNabbuye-Sekandi, Juliet
dc.contributor.authorManabe, Yukari C.
dc.date.accessioned2021-12-15T06:47:11Z
dc.date.available2021-12-15T06:47:11Z
dc.date.issued2011
dc.description.abstractTo identify health facility and patient-specific factors associated with TB treatment default in HIV-infected patients, in a TB clinic on the campus of Mulago National Referral Hospital in Kampala, Uganda. methods Unmatched case–control study between March and May 2009. Cases were TB patients known to have defaulted on their anti-TB treatment, defined as a TB patient who had documented discontinuation of TB medication for two or more consecutive months due to reasons other than physician’s advice and who did not access care at another facility. Controls were TB patients who completed 8 months of anti-TB treatment without interruption of two or more months. Data on health facility-specific factors and individual characteristics were collected using semi-structured questionnaires. results Factors associated with defaulting from TB treatment were: distance from home to clinic (OR 2.22; 1.21–4.06); long waiting time at the clinic (OR 4.18; 2.18–8.02); poor drug availability (OR 4.75; 2.29–9.84); conduct of staff (OR 2.72; 1.02–7.25); lack of opportunity to express feelings (OR 3.47; 1.67–7.21). Other patient-related factors were lack of health education, i.e. not being aware of the duration of treatment or the risk of discontinuing it (OR 5.31; 1.94–14.57); not knowing that TB can be cured (OR 44.11; 13.66–142.41); length of TB treatment (OR 10.77; 5.18–22.41), and side effects of treatment OR 5.53 (2.25–13.61). conclusions Defaulting is influenced by health systems, staff factors, and patient misinformation. Health education on TB directed at patients combined with staff sensitization could help to improve adherence to TB treatment.en_US
dc.identifier.citationElbireer, S., Guwatudde, D., Mudiope, P., Nabbuye‐Sekandi, J., & Manabe, Y. C. (2011). Tuberculosis treatment default among HIV‐TB co‐infected patients in urban Uganda. Tropical Medicine & International Health, 16(8), 981-987.doi:10.1111/j.1365-3156.2011.02800.xen_US
dc.identifier.other10.1111/j.1365-3156.2011.02800.x
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/524
dc.language.isoenen_US
dc.publisherTropical Medicine & International Healthen_US
dc.subjecttreatment defaulten_US
dc.subjecttuberculosis, HIen_US
dc.titleTuberculosis treatment default among HIV-TB co-infected patients in urban Ugandaen_US
dc.typeArticleen_US
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