Solanum anguivi Lam. Fruits: Their Potential Effects on Type 2 Diabetes Mellitus

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dc.contributor.authorNakitto, Aisha Musaazi Sebunya
dc.contributor.authorMuyonga, John H.
dc.contributor.authorByaruhanga, Yusuf Byenkya
dc.contributor.authorWagner, Anika E.
dc.date.accessioned2023-04-05T18:18:38Z
dc.date.available2023-04-05T18:18:38Z
dc.date.issued2021
dc.description.abstractType 2 diabetes mellitus (T2DM) is a complex metabolic disorder of glucose homeostasis associated with a status of insulin resistance, impaired insulin signaling, β-cell dysfunction, impaired glucose and lipid metabolism, sub-clinical inflammation, and increased oxidative stress. Consuming fruits and vegetables rich in phytochemicals with potential antidiabetic effects may prevent T2DM and/or support a conservative T2DM treatment while being safer and more affordable for people from low-income countries. Solanum anguivi Lam. fruits (SALF) have been suggested to exhibit antidiabetic properties, potentially due to the presence of various phytochemicals, including saponins, phenolics, alkaloids, ascorbic acid, and flavonoids. For the saponin fraction, antidiabetic effects have already been reported. However, it remains unclear whether this is also true for the other phytochemicals present in SALF. This review article covers information on glucose homeostasis, T2DM pathogenesis, and also the potential antidiabetic effects of phytochemicals present in SALF, including their potential mechanisms of action.en_US
dc.identifier.citationNakitto, A. M. S., Muyonga, J. H., Byaruhanga, Y. B., & Wagner, A. E. (2021). Solanum anguivi Lam. fruits: Their potential effects on type 2 diabetes mellitus. Molecules, 26(7), 2044.https://doi.org/10.3390/molecules26072044en_US
dc.identifier.issn1420-3049
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8427
dc.language.isoenen_US
dc.publisherMoleculesen_US
dc.subjectglucose homeostasisen_US
dc.subjectoxidative stressen_US
dc.subjectSolanum anguivi fruitsen_US
dc.titleSolanum anguivi Lam. Fruits: Their Potential Effects on Type 2 Diabetes Mellitusen_US
dc.typeArticleen_US
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