Prevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school children aged 5–15 yrs in Wakiso District, Uganda

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dc.contributor.authorNayiga, Irene
dc.contributor.authorOkello, Emmy
dc.contributor.authorLwabi, Peter
dc.contributor.authorNdeezi, Grace
dc.date.accessioned2022-05-28T19:47:44Z
dc.date.available2022-05-28T19:47:44Z
dc.date.issued2017
dc.description.abstractBeta-hemolytic streptococci carrier rates in children living in low-income countries are high ranging from 10 to 50%. Although most of these children are asymptomatic, they are a reservoir and pose a risk of transmission. The aim of this study was to determine the prevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school going children in Wakiso district, Uganda.A cross sectional study targeting children age 5–15 years in primary schools in one sub-county of Wakiso district was carried out. Three hundred and sixty-six children from five primary schools were enrolled and evaluated for group a streptococcus (GAS) carriage. A semi-structured questionnaire was used to collect data that included social demographics, school environment and clinical findings. For every enrolled child a throat swab was taken and cultured for GAS and blood was drawn for anti-streptolysin-O titres. Analysis of data was done using STATA.The prevalence of GAS carriage was 16%. The children with GAS positive cultures were mainly females. The factor associated with GAS carriage was the school location, with peri-urban schools more likely to have children with GAS compared to rural schools; AOR 2.48 (95% CI: 1.01 – 6.11), P = 0.049. There was no significant difference between the characteristic of children with GAS positive verses GAS negative throat swab cultures.There is a high prevalence of GAS pharyngeal carriage among children aged 5–15 years attending primary schools in Wakiso District, Uganda.en_US
dc.identifier.citationNayiga, I., Okello, E., Lwabi, P., & Ndeezi, G. (2017). Prevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school children aged 5–15 yrs in Wakiso District, Uganda. BMC Infectious Diseases, 17(1), 1-8.https://doi.org/10.1186/s12879-017-2353-5en_US
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/3620
dc.language.isoenen_US
dc.publisherBMC Infectious Diseasesen_US
dc.subjectGroup a streptococcus; Carriage; Ugandaen_US
dc.titlePrevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school children aged 5–15 yrs in Wakiso District, Ugandaen_US
dc.typeArticleen_US
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