The Challenge of HIV-1 Antiretroviral Resistance in Africa in the Era of HAART
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Date
2009
Authors
Sendagire, Hakim
Easterbrook, Philippa J.
Nankya, Immaculate
Arts, Eric
Thomas, David
Reynolds, Steven J.
Journal Title
Journal ISSN
Volume Title
Publisher
AIDS reviews
Abstract
Antiretroviral therapy programs in Africa are currently providing treatment for almost two million people. The long-term success of large scale antiretroviral therapy programs in sub-Saharan Africa remains uncertain because of the limited information currently available on rates of virologic failure and selection for drug-resistant variants in the different HIV subtypes. This article provides a comprehensive review of the published literature on the prevalence of primary and secondary HIV drug resistance with different subtypes and in various settings across sub-Saharan Africa.
Description
Keywords
Antiretroviral therapy, ART, Resistance, Africa, Subtypes, Phenotypic, Genotypic
Citation
Sendagire, H., Easterbrook, P. J., Nankya, I., Arts, E., Thomas, D., & Reynolds, S. J. (2009). The challenge of HIV-1 antiretroviral resistance in Africa in the era of HAART. AIDS reviews, 11(2), 59.