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dc.contributor.authorKatabarwa, Moses N.
dc.contributor.authorHabomugisha, Peace
dc.contributor.authorKhainza, Annet
dc.contributor.authorOguttu, David
dc.contributor.authorByamukama, Edson
dc.contributor.authorKatamanywa, James
dc.contributor.authorIsingooma, Thomson
dc.contributor.authorBwenume, Fredrick
dc.contributor.authorNahabwe, Christine
dc.contributor.authorNgabirano, Monica
dc.contributor.authorAkampurira, Paul
dc.contributor.authorBernard, Lauri
dc.contributor.authorUnnasch, Thomas R.
dc.contributor.authorRichards, Frank
dc.date.accessioned2022-01-30T21:42:10Z
dc.date.available2022-01-30T21:42:10Z
dc.date.issued2020
dc.identifier.citationKatabarwa, M. N., Habomugisha, P., Khainza, A., Oguttu, D., Byamukama, E., Katamanywa, J., ... & Richards, F. (2020). Elimination of Simulium neavei–Transmitted Onchocerciasis in Wambabya–Rwamarongo Focus of Western Uganda. The American Journal of Tropical Medicine and Hygiene, 103(3), 1135 doi:10.4269/ajtmh.20-0195.en_US
dc.identifier.other10.4269/ajtmh.20-0195
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1645
dc.description.abstractWambabya–Rwamarongo onchocerciasis focus is one of the eight foci Uganda verified using the WHO verification guidelines. The approach for elimination was twice yearly treatment with ivermectin for every round, treating at least 90% of all the eligible population. This was in combination with vector elimination using Abate® (BASF SE, Limburgerhof, Germany) since elimination nationwide policy was launched. From 2008 to 2013, the program distributed ivermectin with a mean treatment coverage of the ultimate treatment goal (UTG) or eligible population of 91.2%, with a range of 85–96%. In 2009, vector elimination based on ground larviciding had a dramatic impact on the Simulium vectors, as the last fly was observed in October 2009. No more Simulium vectors were observed during a period of at least 7 years, including the 3-year posttreatment surveillance (PTS) until the focus was reclassified as eliminated in August 2017. During the PTS period, none of the 10,578 trapped crabs were found infested with the aquatic stages of the vector. The last infested crab was observed in March 2010, and for at least 7 years, no infested crabs were observed. Serological surveys showed that of 2,978 young children examined in 2013, only one was OV16 positive (0.0%;95% CI: 0–0.21). In 2017, after the PT period, all 3,079 young children examined were negative for OV16(95% CI: 0–0.16). Therefore, entomological and ecological results provided evidence that resulted in the reclassification of WambabyaRwamarongo focus from “transmission interrupted” to “transmission eliminated” with no possibility of recrudescence.en_US
dc.language.isoenen_US
dc.publisherThe American Journal of Tropical Medicine and Hygieneen_US
dc.subjectSimulium neavei–Transmitted Onchocerciasisen_US
dc.subjectWambabya–Rwamarongoen_US
dc.subjectUgandaen_US
dc.titleElimination of Simulium neavei–Transmitted Onchocerciasis in Wambabya–Rwamarongo Focus of Western Ugandaen_US
dc.typeArticleen_US


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