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    Expanded Phase I safety and acceptability study of 6% cellulose sulfate vaginal gel

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    Article (119.3Kb)
    Date
    2005
    Author
    Malonza, Isaac M.
    Mirembe, Florence
    Nakabiito, Clemensia
    Odusoga, Lawrence O.
    Osinupebi, Olubunmi A.
    Hazari, Kamal
    Chitlange, Shanta
    Alia, Mohamed M.
    Callahane, Marianne
    Damme, Lut Van
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    Abstract
    An expanded Phase I trial was performed to assess the safety and acceptability of 6% cellulose sulfate gel (CS) in comparison with K-Y Jelly. Sexually abstinent (cohort I) and sexually active (cohort II) women in India, Nigeria and Uganda applied 3.5 ml of either 6% CS gel or K-Y Jelly for seven consecutive days. Safety was assessed by symptoms and signs (including colposcopy) of genital irritation, review of adverse events, and by changes in vaginal health as assessed by microscopy.
    URI
    https://nru.uncst.go.ug/xmlui/handle/123456789/1389
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    • Medical and Health Sciences [3718]

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