Browsing by Author "Zirimenya,Ludoviko"
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Item Pre-vaccination Schistosoma mansoni and hookworm infections are associated with altered vaccine immune responses: a longitudinal analysis among adolescents living in helminth-endemic islands of Lake Victoria, Uganda(Frontiers in Immunology, 2024-08-29) Natukunda, Agnes; Zirimenya,Ludoviko; Nkurunungi, Gyaviira; Nassuuna, JacentVariations in vaccine responses have been observed between populations. A role for helminth infections has been proposed due to their immunomodulatory properties. In a secondary analysis of data from a randomised trial assessing effects of anthelminthic treatment on vaccine responses, we examined associations between helminth infections at baseline prior to vaccine administration, and vaccine responses among adolescents (9-17 years) in Koome Islands, Lake Victoria, Uganda.