Browsing by Author "Yadesa, Tadele Mekuriya"

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    Antibacterial Prescription and the Associated Factors among Outpatients Diagnosed With Respiratory Tract Infections in Mbarara Municipality, Uganda
    (BMC Pulmonary Medicine, 2021) Muwanguzi, Timothy Eria; Yadesa, Tadele Mekuriya; Agaba, Amon Ganafa
    Respiratory tract infections (RTI) are the second most frequent diagnosis after Malaria amongst Outpatients in Uganda. Majority are Non pneumonia cough and flu which are self-limiting and often do not require antibacterials. However, antibiotics are continuously prescribed for these conditions and are a major contributor to antimicrobial resistance and wastage of health resources. Little is known about this problem in Uganda hence the impetus for the study.To determine the antibacterial prescribing rate and associated factors among RTI outpatients in Mbarara municipality. This was a retrospective cross-sectional study on records of RTI outpatients from 1st April 2019 to 31st March 2020 (prior to the novel corona virus disease pandemic) in four selected public health facilities within Mbarara municipality. A pretested data caption tool was used to capture prescribing patterns using WHO/INRUD prescribing indicators. We used logistic regression to determine factors associated to antibacterial prescribing.A total of 780 encounters were studied with adults (18-59 years) forming the largest proportion of age categories at (337, 43.15%) and more females (444, 56.85%) than men (337, 43.15%). The antibacterial prescribing rate was 77.6% (606) with Amoxicillin the most prescribed 80.4% (503). The prescribing pattern showed an average of 2.47 (sd 0.72) drugs per encounter and the percentage of encounters with injection at 1.5% (24). Drugs prescribed by generic (1557, 79%) and drugs prescribed from essential medicine list (1650, 84%) both not conforming to WHO/INRUD standard; an indicator of possible irrational prescribing. Female gender (adjusted odds ratio [aOR] = 1.51, 95% confidence interval [CI]: (1.06–2.16); 18–59 years age group (aOR = 1.66, 95% CI: 1.09–2.33) and Individuals prescribed at least three drugs were significantly more likely to have an antibacterial prescribed (aOR= 2.72, 95% CI: 1.86–3.98).The study found a high antibacterial prescribing rate especially among patients with URTI, polypharmacy and non-conformity to both essential medicine list and generic name prescribing. This prescribing pattern does not comply with rational drug use policy and needs to be addressed through antimicrobial stewardship interventions, prescriber education on rational drug use and carrying out more research to determine the appropriateness of antibacterial prescribed.
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    Factors associated with relief from acute pain among patients admitted in medical ward of Mbarara Regional Referral Hospital, south western Uganda: A cross-sectional study
    (Public Library of Science, 2025-03) Ojuka, Silas;; Tamukong, Robert;; Yadesa, Tadele Mekuriya
    Acute pain is an understudied subject among patients admitted in medical wards, especially in sub-Saharan Africa. Given that it is one of the commonest causes of hospital admissions, it is necessary to diagnose and adequately treat it in time. Unrelieved acute pain may have negative consequences such as; reduced quality of life, prolonged hospital stays and increased cost of treatment. The purpose of this study was to assess relief of acute pain and factors associated with it in medical ward of Mbarara Regional Referral Hospital, South-Western Uganda. Severity of pain was determined using the Brief Pain Inventory. Adequate drug therapy for acute pain was assessed using the Pain Management Index. Relief from acute pain was considered a change in pain grade from severe to mild or moderate to mild or mild to no pain. This was done by comparing baseline pain grade at enrollment (day one) and follow up pain grade on day two. Multivariate logistic regression was performed to identify associated factors that had statistical significance. Out of 280 patients with acute pain, analgesic drug therapy was adequate for 32 (11.43%) participants while relief from acute pain was achieved among 95 (34%). Multivariate logistic regression showed female gender to be significantly associated with relief from acute pain (adjusted Odds Ratio=1.86; 1.11-3.10 at 95% C.I; p value=0.018). Prevalence of adequacy of analgesic drug therapy for acute pain among patients admitted in medical ward of Mbarara Regional Referral Hospital was low. Proportion of patients with relief from acute pain was also low. Female patients were more likely to experience relief from acute pain compared to their male counterparts.