Browsing by Author "Wabwire, Fred M."

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    Epidemiology of HPV genotypes in Uganda and the role of the current preventive vaccines: A systematic review
    (Infectious Agents and Cancer, 2011) Banura, Cecily; Mirembe, Florence M.; Katahoire, Anne R.; Namujju, Proscovia B.; Mbonye, Anthony K.; Wabwire, Fred M.
    Limited data are available on the distribution of human papillomavirus (HPV) genotypes in the general population and in invasive cervical cancer (ICC) in Uganda. Yet, with the advent of preventive HPV vaccines that target HPV 16 and 18 responsible for causing about 70% of ICC cases in the world, such information is crucial to predict how vaccination and HPV-based screening will influence prevention of ICC. To review the distribution of HPV infection and prevalent genotypes, electronic databases (e.g. PubMed/ MEDLINE and HINARI) were searched for peer reviewed English articles on HPV infection up to November 30, 2010. Eligible studies were selected according to the following criteria: DNA-confirmed cervical or male genital HPV prevalence and genotypes, HPV incidence estimates and HPV seroprevalence among participants.