Browsing by Author "Shi, Xiangyang"

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    Cellulose Nanocrystals in Cancer Diagnostics and Treatment
    (Journal of Controlled Release, 2021) Lugoloobi, Ishaq; Maniriho, Hillary; Jia, Liang; Namulinda, Tabbisa; Shi, Xiangyang; Zha, Yili
    Cancer is currently a major threat to public health, being among the principal causes of death to the global population. With carcinogenesis mechanisms, cancer invasion, and metastasis remaining blurred, cancer diagnosis and novel drug delivery approaches should be developed urgently to enable management and treatment. A dream break-through would be a non-invasive instantaneous monitoring of cancer initiation and progression to fast-track diagnosis for timely specialist treatment decisions. These innovations would enhance the established treatment protocols, unlimited by evasive biological complexities during tumorigenesis. It is therefore contingent that emerging and future scientific technologies be equally biased towards such innovations by exploiting the apparent properties of new developments and materials especially nanomaterials. CNCs as nanomaterials have undisputable physical and excellent biological properties that enhanced their interest as biomedical materials. This article therefore highlights CNCs utility in cancer diagnosis and therapy. Their extraction, properties, modification, in-vivo/in-vitro medical applications, biocompatibility, challenges and future perspectives are precisely discussed.
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    Nanotechnology and Carbon Nanotubes; A Review of Potential in Drug Delivery
    (Macromolecular Research, 2012) Kamalha, Edwin; Shi, Xiangyang; Mwasiagi, Josphat I.; Zeng, Yongchun
    The need for affordable health care costs and the quest for better modes of treatment have increased research in novel drug delivery techniques. Efficient drug delivery systems (DDS) are judged on their ability to perform controlled and targeted drug delivery. Several nanomaterials such as carbon nanotubes (CNTs) are widely being investigated for biomedical use due to their unique properties, as well as several functional groups and incorporated targeting molecules. This review looked at nanotechnology as an emerging field in drug delivery. Several studies and findings with regards to the current functionalization of CNTs for drug delivery were explored. The conclusion reviewed the key notes.