Browsing by Author "Semuyaba, Ibrahim"

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    Community Education Challenges in Young Adults of South Western Uganda
    (Open Journal of Epidemiology, 2015) Kasozi, Keneth Iceland; Echoru, Isaac; Mbiydzenyuy, Elvis Ngala; Kimwise, Aaron; Nansunga, Miriam; Semuyaba, Ibrahim; Kalange, Muhamudu; Ninsiima, Herbert Izo; Muggaga, Kintu; Emorut, Simon Peter
    The aim of this study was to identify the major challenges to community education and any health problem in Bushenyi district of South Western Uganda. Data collection was done through questionnaire and participants were randomly selected. This was a cross-sectional study carried out for a period of three months in 2012. A questionnaire was used to collect data and using onsite observations the responses were validated. A total of 260 participants from 65 homesteads were included in the study from 52 households. 144 were females and 116 males, of which 52.4% of the children were female and the rest male. The mean ± SEM age of females and males was 36 ± 8.6 and 29 ± 8.6 years respectively. In all the homesteads, 71% were headed by an adult male and only 29% were found to be headed by an adult female while none was headed by children. Inferential analysis showed (P = 0.02) that there are more females than male in the homesteads. Majority of the homesteads are being taken care of by women instead of men probably as a result of the high mortalities due to HIV/AIDS in the past decade and above all the movement of most men to urban centers in search of better sources of employment to support their families. Among school going age participant’s i.e. children and adolescents, only 59.6% were found to be attending school. There was no statistical significance (P = 0.16) between school attendance and age. Family responsibilities such as cooking for younger siblings by female participants, obligations on open market days are thought to be secondary limiting factors for community development and livelihood amongst young persons; thus a follow up study would be conducted to assess their associations in this community as this would raise major child abuse concerns which would need to be reported to the legal authorities for follow up.
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    Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster
    (Journal of Complementary and Integrative Medicine, 2020) Ayikobua, Emmanuel Tiyo; Kasolo, Josephine; Kasozi, Keneth Iceland; Eze, Ejike Daniel; Safiriyu, Abass; Ninsiima, Herbert Izo; Kiyimba, Kennedy; Namulema, Jackline; Jjesero, Edward; Ssempijja, Fred; Semuyaba, Ibrahim; Kimanje, Kyobe Ronald; Kalange, Muhamudu; Okpanachi, Alfred Omachonu; Nansunga, Miriam
    The Phosphatase and tensin-induced putative kinase 1 (PINK1B9) mutant for Drosophila melanogaster is a key tool that has been used in assessing the pathology of Parkinsonism and its possible remedy. This research was targeted toward determining the effects of ethanolic extract of propolis, with levodopa therapy in the management of Parkinsonism. The PINK1B9 flies were divided into groups and fed with the different treatment doses of ethanoic extract of propolis. The treatment groups were subjected to 21 days of administration of propolis and the levodopa at different doses after which percentage climbing index, antioxidant activity and lifespan studies were done.Propolis alone improved motor activity, antioxidant and lifespan in Drosophila melanogaster than in PINK1 flies. Propolis in combination with levodopa significantly (P<0.05) improved physiological parameters at higher than lower concentrations in Parkinsonism Drosophila melanogaster demonstrating its importance in managing side effects associated with levodopa. Propolis is a novel candidate as an alternative and integrative medicinal option to use in the management of Parkinsonism in both animals and humans at higher concentrations.