Browsing by Author "Otita, Morgan"

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    Blood Culture Testing Outcomes among Non-Malarial Febrile Children at Antimicrobial Resistance Surveillance Sites in Uganda, 2017–2018
    (Tropical medicine & infectious disease, 2018) Kisame, Rogers; Najjemba, Robinah; Griensven, Johan van; Kitutu, Freddy Eric; Takarinda, Kudakwashe; Thekkur, Pruthu; Delamou, Alexandre; Walwema, Richard; Kakooza, Francis; Mugerwa, Ibrahim; Sekamatte, Musa; Robert, Kimera; Katairo, Thomas; Opollo, Marc Sam; Otita, Morgan; Lamorde, Mohammed
    Blood culture (BC) processes are critical to the utility of diagnostic testing, bloodstream infection (BSI) management, and antimicrobial resistance (AMR) surveillance. While Uganda has established BC guidelines, often laboratory practice does not meet the desired standards. This compromises pathogen recovery, reliability of antimicrobial susceptibility testing, and diagnostic test utility. This study assessed laboratory BC process outcomes among non-malarial febrile children below five years of age at five AMR surveillance sites in Uganda between 2017 and 2018. Secondary BC testing data was reviewed against established standards. Overall, 959 BC specimens were processed. Of these, 91% were from female patients, neonates, infants, and young children (1–48 months). A total of 37 AMR priority pathogens were identified; Staphylococcus aureus was predominant (54%), followed by Escherichia coli (19%). The diagnostic yield was low (4.9%). Only 6.3% of isolates were identified. AST was performed on 70% (18/26) of identified AMR priority isolates, and only 40% of these tests adhered to recommended standards. Interventions are needed to improve laboratory BC practices for effective patient management through targeted antimicrobial therapy and AMR surveillance in Uganda. Further research on process documentation, diagnostic yield, and a review of patient outcomes for all hospitalized febrile patients is needed.
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    Impacts and Lessons Learnt From Local Production of WHO Recommended Alcohol Based Hand Rub During Covid-19 Pandemic in Uganda
    (Research Square, 2020) Tusabe, Fred; Otita, Morgan; Kesande, Maureen; Twinomugisha, Fred
    The Government of Uganda through the Ministry of Health and other partners have promoted hand washing and hand rubbing using ABHS as one of the key preventive measures against person-to-person spread of the Covid-19 virus. The people of Uganda have greatly heeded to these messages and as a result, the demand for ABHS has increased because of high consumption rates. A district multi modal design was established in 2019 in Kabarole and Kasese districts in Western Uganda Part of the strategy was to set up an ABHS production units. The prevailing COVID-19 outbreak has instigated set up at centrally located Kasangati HCIV. We analysed the demand and production of ABHS produced before and during the COVID-19 outbreak.