Browsing by Author "Nyeko, Richard"

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    Care Burden and Coping Strategies among Caregivers of Paediatric HIV/AIDS in Northern Uganda: A Cross-Sectional Mixed-Method Study
    (AIDS Research and Treatment, 2021) Mujjuzi, Ibrahim; Mutegeki, Paul; Nabuwufu, Sarah; Wosukira, Ashim; Namata, Fazirah; Alayo, Patience; Amanya, Sharon B.; Nyeko, Richard
    Family caregivers provide the bulk of care to children living with HIV. +is places an enormous demand and care burden on the caregivers who often struggle to cope in various ways, some of which may be maladaptive. +is may adversely affect their quality of care. Very little literature exists in resource-limited contexts on the burden of care experienced by caregivers on whom children living with HIV/AIDS depend for their long-term care. We assessed care burden and coping strategies among the caregivers of paediatric HIV/AIDS patients in Lira district, northern Uganda. Methods. A mixed-method cross-sectional study was conducted among 113 caregivers of paediatric HIV patients attending the ARTclinic at a tertiary healthcare facility in Lira district, northern Uganda. A consecutive sampling method was used to select participants for the quantitative study, while 15 respondents were purposively sampled for the qualitative data. Quantitative data were collected using standard interviewer-administered questionnaires, while in-depth interview guides were used to collect qualitative data. Data were entered, cleaned, and analysed using SPSS version 23. Qualitative data were analysed thematically. Results. +emajority of the caregivers, 65.5% (74), experienced mild-to-moderate burden. +e mean burden scores significantly differed by caregivers’ age (P � 0.017), marital status (P � 0.017), average monthly income (P � 0.035), and child’s school attendance (P � 0.039). Accepting social support, seeking spiritual support, and reframing were the three most commonly used strategies for coping. Marital status and occupation were, respectively, positively and negatively correlated with information-seeking as a coping strategy, while monthly income was positively correlated with psychosocial support as a strategy. Seeking community support was negatively correlated with the duration of the child’s care. Conclusions. Our findings show that care burden is a common problem among the caregivers of children living with HIV in the study context.
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    Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial
    (BMC medicine, 2013-03-14) Maitland, Kathryn; Kiguli,Sarah; Olupot-Olupot, Peter; Akech, Samuel O.; Opoka, Robert O.; Nyeko, Richard; Nteziyaremye, Julius
    Early rapid fluid resuscitation (boluses) in African children with severe febrileillnesses increases the 48-hour mortality by 3.3% compared with controls (nobolus). We explored the effect of boluses on 48-hour all-cause mortality byclinical presentation at enrolment, hemodynamic changes over the first hour, andon different modes of death, according to terminal clinical events. We hypothesizethat boluses may cause excess deaths from neurological or respiratory eventsrelating to fluid overload.