Browsing by Author "Namulindwa, Angella"

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    Assessment of Health Supply Chain Risks in Uganda: The Case of Uganda Health Supply Chain Project
    (V, 2020) Wasswa, John Hans; Namulindwa, Angella
    This study aimed at assessing risks affecting Health supply chains in Uganda using a case of Uganda Health Supply Chain project. The theoretical framework onto which this study was anchored was the normative decision theory of risk management. A cross sectional study design was adopted employing the quantitative research approach. A sample population of 196 was used and primary data was collected using self-administered questionnaires and analyzed using STATA statistical program. Descriptive data was presented in form of graphs and frequency distribution tables. It was later analyzed and interpreted using percentages, frequencies, means, and standard deviations. The study results revealed that the greatest health supply chain risks faced by health supply chain programs in Uganda were; Financial-related risks such as cost overruns; and End user-related risks such as poor quality health commodities, poor feedback mechanisms and loss of patient lives. Other major risks discovered by the study included demand and supply-relate drisks resulting from supplier unpredictability such as stock outs; Procurement-related risks such as long lead-times and inadequate technical input; and distribution and Storage-related risks. Environmental-related risks such as accidents, bad weather and political instability were the least faced risks. The study concluded that health supply chains in Uganda are troubled by a multitude of risks, and therefore the study recommended that,after a clear understanding of risks affecting health supply chains has been uncovered, carefully-tailored standard risk management processes can be established within health supply chain projects to improve the functionality of Uganda’s health supply chain management systems.
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    Prevalence and factors associated with adverse drug events among patients on dolutegravir‑based regimen at the Immune Suppression Syndrome Clinic of Mbarara Regional Referral Hospital, Uganda: a mixed design study
    (AIDS Research and Therapy, 2022) Namulindwa, Angella; Wasswa, John Hans; Muyindike, Winnie; Tamukong, Robert; Oloro, Joseph
    In low income countries such as Uganda progress has been made towards achieving the United Nations AIDS programme 95-95-95 target however efforts are still impeded by pretreatment drug resistance and adverse drug events (ADEs) hence introduction of dolutegravir-based antiretroviral therapy as first-line treatment due to a higher genetic barrier to resistance, better tolerability and safety profile. However, recent studies have raised concerns regarding its safety in real-clinical settings due to ADEs and being a recently introduced drug there is need to actively monitor for ADEs, hence this study aimed to establish the prevalence and factors associated with ADEs among patients on dolutegravir-based regimen at the Immune Suppression Syndrome (ISS) Clinic- Mbarara Regional Referral Hospital (MRRH). Methods: A mixed design study was conducted at ISS Clinic-MRRH among 375 randomly selected patients who had been exposed to DTG-based regimen for at-least 12 weeks. These were interviewed to obtain data on sociodemographics, dietary habits and their files reviewed for ADEs. Data entry was done using Epi-data 3.0 and exported to SPSS 25.0 for analysis. Prevalence was determined as a percentage, and ADE associated factors assessed using bivariate analysis, those found significant were further subjected to multivariate analysis and considered significant at P < 0.05. Results: The prevalence of ADEs among patients on DTG-based regimen was found to be 33.1% (124/375) with 5.6% (7/124) participants discontinued from treatment due ADEs, 4 due to hyperglycemia and 3 liver toxicity. The commonly experienced ADE was allergy at 36.3%. Male sex (AOR 1.571, 95% CI 1.433–1.984), WHO stage one at entry to care (AOR 4.586, 95% CI 1.649–12.754), stage two (AOR 4.536, 95% CI 1.611–12.776), stage three (AOR 3.638, 95% CI 1.262–10.488), were significantly associated with ADEs. Patients with undetectable viral load at initiation of DTG-based regimen were 67.6% less likely to experience ADEs (AOR = 0.324, 95% CI 0.1167–0.629). Conclusion: This study reports a prevalence of 33.1% of ADEs among patients on DTG-based regimen. The most commonly experienced ADE was allergy. Male sex, early HIV disease stage at entry into care and detectable viral load at initiation of DTG-based regimen
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    Risk Management and Performance of Health Supply Chain Projects in Uganda. The Case of Uganda Health Supply Chain Project
    (International Journal of Science and Research (IJSR), 2018) Wasswa, John Hans; Kwatampora, Rose; Bwanika, Godfrey; Namulindwa, Angella
    This study aimed at assessing the effect of risk management on performance of Health supply chain projects in Uganda using a case of Uganda Health Supply Chain project. The specific objectives were; to determine the effect of risk identification on the performance of health supply chain projects in Uganda; assess the effect of risk analysis on the performance of health supply chain projects in Uganda; investigate the extent to which planning for risk management affects the performance of health supply chain projects in Uganda and lastly determine the extent to which risk response and control affect performance of health supply chain projects in Uganda. The study was based on the normative decision theory of risk management and the positivism research philosophy. It employed a cross-sectional study design and adopted both quantitative and qualitative approaches. A total sample population of 196 was used. Primary data was collected using self-administered questionnaires for quantitative data and analyzed using STATA while qualitative data was collected using an interview guide and analyzed using the content analysis method. In this study, four hypotheses were tested using the logistic regression technique employing the p-value and odds ratio approach. Findings revealed a good understanding of the risk management concept among a majority of the respondents, but however, there was a low adoption of standard risk management practices. The study further revealed that a majority of the investigated practices had a significant effect on the level of time, cost and quality performance of health supply chain projects in Uganda. The study concluded that performance of health supply chain projects in Uganda has been below average due to low adoption of standard risk management practices. The study recommended prioritizing risk management high on the project’s management agenda by all supply chain projects in Uganda