Browsing by Author "Kateregga, John N."

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    Effect of Antiretroviral Drugs on the Renal Function of HIV Seropositive Patients attending ISS Clinic of Mulago Hospital, Uganda
    (Ann Biotechnol, 2018) Kateregga, John N.; Atuheire, Collins; Nalunga, Justine; James, Ndukui G.
    Highly Active Antiretroviral Therapy (HAART) consisting of at least three active drugs against HIV infection has improved HIV/AIDS management since their inception. However, alterations of lipid metabolism due to HAART can result into secondary diabetic and hypertensive renal damage. This study was carried out to assess the effect of antiretroviral drugs on the renal function of HIV seropositive patients by determining the serum levels of Creatinine, Urea and Electrolytes (Na, K, and Cl) of the patients on treatment.
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    Inorganic Pollutants in Edible Grasshoppers (Ruspolia Nitidula) of Uganda and their Major Public Health Implications
    (African Health Sciences, 2019) Kasozi, Keneth Iceland; Namazi, Catherine; Basemera, Elizabeth; Atuheire, Collins; Odwee, Ambrose; Majalija, Samuel; Kateregga, John N.
    Inorganic contamination of food products is associated with adverse health effects, however, information on grasshoppers in Africa is sparse. The objective of the study was to determine antioxidant, heavy metal and food safety status of edible grasshoppers of Uganda. A cross-sectional study was conducted in central and southwestern Uganda, in which a questionnaire was administered to grasshopper harvesters. Grasshopper samples were collected from each harvesting point and analyzed in the laboratory for antioxidant and heavy metal content i.e. Lead (Pb), Chromium (Cr), Zinc (Zn) and Cadmium (Cd) using atomic absorbance spectrometric (AAS) method on the heads and abdomen of the insects. Major antioxidants were Catalase > Glutathione > Glutathione peroxidase. In addition concentrations of heavy metals were in the order of Pb > Cr > Zn > Cd in the heads and abdomens of the grasshoppers. Pb concentrations were found to be higher in the heads than the abdomens and the carcinogenic potential of the grasshoppers was over 10 times over the recommended levels. Grasshoppers were found not to be safe especially in children due to their small body weight in comparison to adults. Pb poisoning in the Ugandan children would be propagated through contaminated grasshoppers.