Browsing by Author "Kamulegeya, Adriane"

Now showing 1 - 5 of 5
  • Thumbnail Image
    Item
    Mosquito-Borne Arboviruses in Uganda History, Transmission and Burden
    (Clinics, 2009) Kamulegeya, Adriane; Lakor, Francis; Kabenge, Kate; Mayanja, Martin N.
    To investigate the epidemiological characteristics of maxillofacial fractures and associated fractures in patients seen in the Oral Surgery Unit of Mulago Hospital, Kampala, Uganda. A six-month prospective study was conducted. Data collected included socio-demographic factors, type and etiology of injury, additional fractures, and post-surgery complications. One hundred thirty-two (132) cases ranging from 5–70 yrs of age were reported, with a male: female ratio of 7.7:1. The 21–30 yr age group was the largest, comprising 51.51% of cases (n=68). Road traffic accidents contributed to 56.06% (n=74) of fractures. In total, 66% of the sample (n=87) suffered isolated mandibular fractures. Symphyseal and maxillary fractures were the most common mandibular and mid-facial fractures, respectively. Among associated fractures, the femur was most affected. A total of 39 (29.54%) of patients had post-operative complications, of which infection accounted for 48.71% (n= 19), and malocclusion accounted for 17.94% (n=7). Anticipated changes in maxillofacial trauma trends necessitate regular epidemiologic studies of facial fractures to allow for development and implementation of timely novel preventive measures.
  • Thumbnail Image
    Item
    Oral Maxillofacial Fractures Seen at a Ugandan Tertiary Hospital: A Six-Month Prospective Study
    (Clinics, 2009) Kamulegeya, Adriane; Lakor, Francis; Kabenge, Kate
    A six-month prospective study was conducted. Data collected included socio-demographic factors, type and etiology of injury, additional fractures, and post-surgery complications. One hundred thirty-two (132) cases ranging from 5–70 yrs of age were reported, with a male: female ratio of 7.7:1. The 21–30 yr age group was the largest, comprising 51.51% of cases (n=68). Road traffic accidents contributed to 56.06% (n=74) of fractures. In total, 66% of the sample (n=87) suffered isolated mandibular fractures. Symphyseal and maxillary fractures were the most common mandibular and mid-facial fractures, respectively. Among associated fractures, the femur was most affected. A total of 39 (29.54%) of patients had post-operative complications, of which infection accounted for 48.71% (n= 19), and malocclusion accounted for 17.94% (n=7). Anticipated changes in maxillofacial trauma trends necessitate regular epidemiologic studies of facial fractures to allow for development and implementation of timely novel preventive measures.
  • Thumbnail Image
    Item
    Public knowledge about oral cancer in Uganda: a free dental camp experience
    (Journal of health research, 2019) Nabirye, Rose C.; Kamulegeya, Adriane
    The purpose of this paper is to assess the levels of awareness and knowledge about oral cancer, its causes and or risk factors among Ugandan patients seeking oral healthcare. Design/methodology/approach – This was a cross-sectional study on adult patients who attended a free dental camp. An assistant-administered questionnaire either in English or Luganda was provided to every even-numbered registered adult who consented to participate in the study. Information on demographics and known risk factors for oral cancer were captured. The two knowledge questions on oral cancers were scored by adding up all the correctly identified causes, non-causes and risk factors then scored out of the total. Data analysis was done by calculating proportions, Student’s’ t-tests and χ2 tests with significant p-value set at 0.05. Findings – The results showed a low level ofawareness/knowledge about oral cancer in studied population. In total, 60 percent and less than 50 percent of respondents identified smoking and alcohol use as risk factors for oral cancer, respectively. Majority of respondents (88.8 percent) would seek help from medical personnel if diagnosed with oral cancer. Screening for cancer was low despite awareness and knowledge that it improves the chances of successful treatment. Research limitations/implications – Emphasis on risk factors including alcohol use in public health messages, use of mass media, religious and community leaders to disseminate messages to the communities and further research were recommended. Practical implications – We need to emphasize the role of alcohol in oral cancer causation just as we do for tobacco consumption. Originality/value – No study has been conducted in Uganda on the level of awareness yet the incidence of the disease and use of high-risk products are rising
  • Thumbnail Image
    Item
    Smell and Taste Symptoms among Patients with Mild and Moderately Severe COVID-19 Infection in Uganda
    (OTO open, 2022) Byaruhanga, Richard; Kabagenyi, Fiona; Kagga, Douglas Ssenyonjo; Ndoleriire, Christopher; Kamulegeya, Adriane; Ssemwogerere, Lamech; Kiguba, Ronald; Kirenga, Bruce; Kakande, Emily
    Patients with coronavirus disease 2019 (COVID-19) may present with smell/taste dysfunctions in addition to the most frequent symptoms (fever, cough, and shortness of breath) or as the first symptom or even the only symptom. There is paucity of documentation of prevalence and characteristics of smell/taste dysfunction in COVID-19 in sub-Saharan Africa. The aim of this study was to determine the prevalence of smell/taste symptoms in our setting to institute local evidence-based practice.
  • Thumbnail Image
    Item
    Survival and associated factors among patients with oral squamous cell carcinoma (OSCC) in Mulago hospital, Kampala, Uganda
    (CrossMark, 2018) Asio, Juliet; Kamulegeya, Adriane; Banura, Cecily
    Abstract Background: Despite improvements in diagnosis and patient management, survival and prognostic factors of patients with oral squamous cell carcinoma (OSCC) remains largely unknown in most of Sub Saharan Africa. Objective: To establish survival and associated factors among patients with oral squamous cell carcinoma treated at Mulago Hospital Complex, Kampala. Methods: We conducted a retrospective cohort study among histologically confirmed oral squamous cell carcinoma (OSCC) patients seen at our centre from January 1st 2002 to December 31st 2011. Survival was analysed using Kaplan-Meier method and comparison between associated variables made using Log rank-test. Cox proportional hazards model was used to determine independent predictors of survival. P-values of less than 0.05 were considered statistically significant. Results: A total of 384 patients (229 males and 155 females) were included in this analysis. The overall mean age was 55.2 (SD 4.1) years. The 384 patients studied contributed a total of 399.17 person-years of follow-up. 111 deaths were observed, giving an overall death rate of 27.81 per 100 person-years [95% CI; 22.97–32.65]. The two-year and five-year survival rates were 43.6% (135/384) and 20.7% (50/384), respectively. Tumours arising from the lip had the best five-year survival rate (100%), while tumours arising from the floor of the mouth, alveolus and the gingiva had the worst prognosis with five-year survival rates of 0%, 0% and 15.9%, respectively. Independent predictors of survival were clinical stage (p = 0.001), poorly differentiated histo-pathological grade (p < 0.001), male gender (p = 0.001), age > 55 years at time of diagnosis (p = 0.02) and moderately differentiated histo-pathological grade (p = 0.027). However, tobacco & alcohol consumption, tumour location and treatment group were not associated with survival (p > 0.05). Conclusions: The five-year survival rate of OSCC was poor at 20.7%. Male gender, late clinical stage at presentation, poor histo-pathological types and advanced age were independent prognostic factors of survival. Early detection through screening and prompt treatment could improve survival. Keywords: Oral squamous cell carcinoma, Uganda, Survival, Clinical-pathological presentation