Browsing by Author "Egede, Leonard E."

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    Age and Gender Differences in Trends and Impact of Depression on Quality of Life in the United States, 2008-2016
    (Women's Health Issues, 2021) Anguzu, Ronald; Nagavally, Sneha; Dawson, Aprill Z.; Walker, Rebekah J.; Egede, Leonard E.
    We aimed to examine age and gender differences in the relationship between depression and quality of life among United States adults. Medical Expenditure Panel Survey data for 2008 to 2016 on 227,663 adults were analyzed. The dependent variable, quality of life, included physical component summary scores and mental component summary scores from the Short Form Health Survey. The key independent variable, depression, was measured using the two-item Patient Health Questionnaire. General linear regression models examined the relationship between quality of life and depression. Models were adjusted for individual and environmental characteristics, symptom status, functional and biological status, and health perceptions and were stratified by gender and age. In adjusted models, mental component summary scores were significantly lower among those with depression compared with those without depression (β = –0.39; 95% confidence interval [CI], 0.38 to –1.16) and lower among women compared with men (β = –0.10; 95% CI, 0.10 to –1.31). Models stratified by gender and age found women with depression ages 40 to 64 (β = –0.07; 95% CI, 0.07 to –0.20) and 65 or older (β = –0.08; 95% CI, 0.08 to –0.24) had significantly lower physical component summary scores compared with those without depression. Among men with depression, those ages 18 to 39 (β = –0.03; 95% CI, 0.03 to –0.10) and 40 to 64 (β = –0.09, 95% CI, 0.08 to –0.26) had lower physical component summary scores compared with those without depression. Women and men of all ages with depression had significantly lower mental component summary scores compared with those without depression. Public health interventions and clinical approaches to address depression in women and men should target functional status in men and perceptions of health in women.
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    Contraception utilization in women with pregestational diabetes
    (The European Journal of Contraception & Reproductive Health Care, 2022) Walker, Shannon L.; Anguzu, Ronald; Egede, Leonard E.; Palatnik, Anna
    Cross-sectional data on women aged 18–44 years from 2011 to 2017 National Survey of Family Growth (NSFG) was analysed. Maternal diabetes was defined as the presence of pre-gestational type 1 or type 2 diabetes. Bivariate and multiple logistic regression analyses were run to evaluate the association between the use of contraception and by contraception type: permanent, long-acting reversible contraception (LARC), other hormonal method, other non-hormonal method, and none, and maternal diabetes status, controlling for relevant covariates. Among the total study sample of 28,454, 1344 (4.7%) had pregestational diabetes. Unadjusted analysis showed women with a history of pregestational diabetes were more likely to use permanent contraception following pregnancy (58.0% vs. 38.7%, p < 0.001) or no contraception (27.2% vs. 24.5%, p < 0.001), but less likely to use LARC (3.4% vs. 11.7%, p < 0.001), other hormonal contraception (4.1% vs. 8.9%, p < 0.001), or other non-hormonal contraception (7.2% vs. 16.4%, p < 0.001). In adjusted analyses, permanent (aOR 1.62, 95% CI 0.72–2.26) remained significant, however the differences were no longer statistically significant: LARC (aOR 0.34, 95% CI 0.12–1.00); other hormonal (aOR 0.61, 95% CI 0.27–1.35); other non-hormonal (aOR 0.59, 95% CI 0.25–1.43); and None (aOR 1.11, 95% CI 0.65–1.89). In this analysis, we found that women with pregestational diabetes were more likely to use permanent contraception methods compared to women without pregestational diabetes; however over a quarter of women with pregestational diabetes did not use contraception between pregnancies.