Nakubulwa, SarahKaye, Dan K.Bwanga, FreddieMbona Tumwesigye, NazariusMirembe, Florence M.2022-01-212022-01-212015Nakubulwa, S., Kaye, D. K., Bwanga, F., Tumwesigye, N. M., & Mirembe, F. M. (2015). Genital infections and risk of premature rupture of membranes in Mulago Hospital, Uganda: a case control study. BMC research notes, 8(1), 1-9. DOI 10.1186/s13104-015-1545-610.1186/s13104-015-1545-6https://nru.uncst.go.ug/xmlui/handle/123456789/1391Inflammatory mediators that weaken and cause membrane rupture are released during the course of genital infections among pregnant women. We set out to determine the association of common genital infections (Trichomonas vaginalis, syphilis, Neisseria gonorrhea, Chlamydia trachomatis, Group B Streptococcus, Bacterial vaginosis, Herpes Simplex Virus Type 2 and candidiasis) and premature rupture of membranes in Mulago hospital, Uganda. Methods: We conducted an unmatched case–control study among women who were in the third trimester of pregnancy at New Mulago hospital, Uganda. The cases had PROM and the controls had intact membranes during latent phase of labour in the labour ward. We used interviewer-administered questionnaires to collect data on sociodemographic characteristics, obstetric and medical history. Laboratory tests were conducted to identify T. vaginalis, syphilis, N. gonorrhea, C. trachomatis, Group B Streptococcus, Bacterial vaginosis, Herpes Simplex Virus Type 2 (HSV-2) and candidiasis. Logistic regression models were used to estimate the odds ratios (OR) and 95 % CI of the association between genital infections and PROM.enGenital infectionsPremature rupture of membranes (PROM)RiskUgandaArticle